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ISSN 2007-6509 (Print)
Órgano oficial de la Asociación Mexicana de Medicina Transfusional A.C.

2010, Number S1

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Rev Mex Med Transfus 2010; 3 (S1)

Harvesting of stem cells in children

Aguilar ED, Lordmendez JD

Language: Spanish
References: 10
Page: 71-74
PDF size: 181.74 Kb.


ABSTRACT

Background: The hematopoietic stem cells trasplantación of peripheral blood, is a benign alternative of treatment for patients with certain diseases of malignant type or hemopatologías. It offers advantages like the facility in the harvesting when it is realized by expert personnel, under risk during the procedure and faster hematological recovery. In the paediatric patients considerations are due to make special. Methods: Phase pre-harvesting: Conditions of patient donor/: Weight Sanguineous group Venous accesses Characteristics of the cellular separator: Type of flows. Extracorporeal volume. Speeds of/return extraction. Additional routes. Phase of harvesting: Beginning of the harvesting Anticoagulation. Results: The harvesting begins with 5 to 20 cells CD34+ microlitre in peripheral blood. ACD-A was used (citrate). For aphaeresis of great volume the combination of ACD-A with Heparina and in both continuous infusion of Gluconato of calcium was used. Conclusion: The number of procedures to realize is variable and will depend on the success of the mobilization, of the final dose of the harvest calculated in relation to the weight of the patient, which means that it is possible that 2 or 3 procedures are even realized until a second cycle. The harvestings will conclude until having reports of final harvest and the therapeutic dose has been obtained.


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