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Colegio de Medicina Interna de México.

2009, Number 2

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Med Int Mex 2009; 25 (2)

Thrombocytopenia: a case report and literature review

Carrillo ER, Morales VN, Ramírez RFJ

Language: Spanish
References: 29
Page: 163-168
PDF size: 440.25 Kb.


ABSTRACT

Pseudotrombocitopenia unrecognized entity with an incidence of 0.09% to 1.9%. (1) It is secondary to the aggregation of platelets in vitro mediated by antibodies that can be EDTA or citrate dependent or both. It is a phenomenon caused by auto platelet antibodies that behave like cold agglutinins EDTA dependent. Antibodies are usually IgG (IgG1 subclasses, IgG2, IgG3, IgG4) although both have been described as IgA IgM antibodies directed against the complex glycoprotein IIb / IIIa of the platelet membrane. It has been associated with sepsis, cancer, cardiac surgery and drugs.


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