2008, Number 5
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Med Int Mex 2008; 24 (5)
Paradoxical embolism in central nervous system, case report and literature review
Carrillo ER, Sánchez GJR
Language: Spanish
References: 24
Page: 361-365
PDF size: 253.70 Kb.
ABSTRACT
A common cause of paradoxical embolism at central nervous system is patent foramen ovale. We report a case of 64 years old male admitted at Intensive Care Unit because of rostrocaudal deterioration secondary to bilateral temporoparietal infracts. Echocardiography reveals a patent foramen ovale of 4 to 5 mm and interatrial septum aneurysm, which was diagnosed as paradoxical embolism due to its bilateral ischemic events. Paradoxical embolism associated to patent foramen ovale is an important cause of cerebral vascular events, frequently unilateral and repetitive. Bilateral events, as this, are rare and have bad prognosis. To adequately establish diagnose, timely treat it, and avoid repetitive ischemic events it is important to have a high level of suspect and differential diagnose.
REFERENCES
Hagen PT, Scholz DG, Edwards WD. Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clin Proc 1984;59:17-20.
Kerut EK, Norfleet WT, Plotnick GD, Giles TD. Patent foramen ovale: a review of associated conditions and the impact of physiological size. J Am Coll Cardiol 2001;38:613-23.
Mas JL, Arquizan C, Lamy C, Patent Foramen Ovale and Atrial Septal Aneurysm Study Group. Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med 2001;345:1740-6.
Thompson T, Evans W. Paradoxical embolism. Q J Med 1930;23:135-50.
Lechat P, Mas JL, Lascault G, Loron P, et al. Prevalence of patent foramen ovale in patients with stroke. N Engl J Med 1988;318:1148-52.
Webster MW, Chancellor AM, Smith HJ. Patent foramen ovale in young stroke patients. Lancet 1988;2:11-12.
Di Tullio M, Sacco RL, Gopal A, Mohr JP, Homma S. Patent foramen ovale as a risk factor for cryptogenic stroke. Ann Intern Med 1992;117:461-5.
Gilbert SG. Pictorial human embryology. 1th ed. Seattle: University of Washington Press, 1989;pp:60-79.
Agmon Y, Khandheria BK, Meissner I, Gentile F, et al. Comparison of frequency of patent foramen ovale by transesophageal echocardiography in patients with cerebral ischemic events versus in subjects in the general population. Am J Cardiol 2001;88:330-2.
Silver MD, Dorsey JS. Aneurysms of the septum primum in adults. Arch Pathol Lab Med 1978;102:62-65.
Hanley PC, Tajik AJ, Hynes JK. Diagnosis and classification of atrial septal aneurysm by two-dimensional echocardiography: report of 80 consecutive cases. J Am Coll Cardiol 1985;6:1370- 82.
Mugge A, Daniel WG, Angermann C. Atrial septal aneurysm in adult patients: a multicenter study using transthoracic and transesophageal echocardiography. Circulation 1995;91:2785- 92.
Heckmann JG, Niedermeier W, Brandt-Pohlmann M, Hilz MJ, et al. Detektion eines offenen Foramen ovale: Transösophageale Echokardiographie und transkranielle Dopplersonographie mit Ultraschallkontrastmittel sind “ergänzende, nicht konkurrierende Methoden.” Med Klin (Munich)1999;94:367-70.
Goldstein LB, Adams R, Becker K. Primary prevention of ischemic stroke: a statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation 2001;103:163-82.
Homma S, Di Tullio MR, Sacco RL, Mihalatos D, et al. Characteristics of patent foramen ovale associated with cryptogenic stroke: a biplane transesophageal echocardiographic study. Stroke 1994;25:582-6.
Overell JR, Bone I, Lees KR. Interatrial septal abnormalities and stroke: a meta-analysis of case-control studies. Neurology 2000;55:1172-9.
Sacco RL, Ellenberg JH, Mohr JP. Infarcts of undetermined cause: the NINCDS Stroke Data Bank. Ann Neurol 1989;25:382-90.
Sacco RL, Shi T, Zamanillo MC, Kargman DE. Predictors of mortality and recurrence after hospitalized cerebral infarction in an urban community: the Northern Manhattan Stroke Study. Neurology 1994;44:626-34.
Pell AC, Hughes D, Keating J, Christie J, et al. Brief report: fulminating fat embolism syndrome caused by paradoxical embolism through a patent foramen ovale. N Engl J Med 1993;329:926-9.
Ranoux D, Cohen A, Cabanes L, Amarenco P, et al. Patent foramen ovale: is stroke due to paradoxical embolism? Stroke 1993;24:31-34.
Martin F, Sanchez PL, Doherty E. Percutaneous transcatheter closure of patent foramen ovale in patients with paradoxical embolism. Circulation 2002;106:1121-6.
Falk V, Walther T, Krankenberg H, Mohr FW. Trapped thrombus in a patent foramen ovale. Thorac Cardiovasc Surg 1997;45:90-92.
Caes FL, Van Belleghem YV, Missault LH, Coenye KE, Van Nooten GJ. Surgical treatment of impending paradoxical embolism through patent foramen ovale. Ann Thorac Surg 1995;59:1559-61.
Hausmann D, Mugge A, Daniel WG. Identification of patent foramen ovale permitting paradoxic embolism. J Am Coll Cardiol 1995;26:1030-8.