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Boletín Médico del Hospital Infantil de México

2010, Number 4

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Bol Med Hosp Infant Mex 2010; 67 (4)

Conditions associated with mortality in neonates weighing ‹ 1000 g at the Obstetric-Gynecology Hospital, Unit N° 23, Monterrey, Mexico (2005-2006)

Padilla MYM, Hernández HRJ

Language: Spanish
References: 70
Page: 335-343
PDF size: 312.45 Kb.


ABSTRACT

Background. Mortality in neonates ‹1 000 g has decreased since the 1970s until now from 90% to 55%, but neurological sequelae and hospital stay have increased. We undertook this study in order to determine the prevalence and etiology of mortality in neonates ‹1 000 g in an Ob-Gyn Unit of the IMSS.
Methods. Causes of death in neonates weighing ‹1 000 g were obtained from hospital registries using dispersion, rates and proportions.
Results. During a 1-year period, 18 952 neonates were born; 152 (0.8%) weighed ›1 000 g and 98(64%) did not survive. There were 54 (55.1%) males and 44 (44.9%) females (1.2:1). The mean weight was 760 g, and mean gestational age was 26 weeks (range: 22-35 weeks). The principal causes of deaths were immaturity in 28/98 cases (28%), intracranial hemorrhage (ICH) in 22/98 (22%), sepsis in 17/98 (17%), pulmonary hemorrhage in 9/98 (9%) and multiple organ failure in 3/98 (3%).
Conclusion. Mortality in neonates with very low birth weight (VLBW, ‹1 000 g) was 64%. Immaturity, ICH and sepsis were the main causes of death. Half of these deaths occurred during the first 48 h of life.


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