2010, Number 2
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Rev Mex Anest 2010; 33 (2)
Intraoperative sedation with dexmedetomidine. Its effect on consumption of other drugs in the radiofrequency saphenous ablation
Ramírez-Guerrero JA, Bueno-Albores S, Dávila-Quesada AE, Gutiérrez-Sougarret B, Piñón-Lozano R, Piñón-Holt D
Language: Spanish
References: 40
Page: 74-78
PDF size: 183.48 Kb.
ABSTRACT
We conducted a retrospective and prospective study to compare the effects of Dexmedetomidine (Dx) on the use of intravenous anesthetics, sedation level, hemodynamic changes, postoperative pain, nausea and vomiting.
Methods: Seventy-eight ASA I-III patients scheduled for radiofrecuency ablations of saphenous vein with local anesthetics were included, 38 received Dx 1 µg/kg for 10 minutes. Maintenance was with midazolam, fentanyl and propofol for control of pain and level ≤ 2 sedation (OOA).
Results: Demographic data were similar in both groups. The Dx group resulted in a significant reduction in use of midazolam and propofol, without changes in use of fentanyl. In 2007, 85% received propofol and in 2008 only 33% needed this. Dx resulted in a significant decrease in heart rate.
Conclusions: Dx used during radiofrecuency ablations of saphenous veins reduced the use of midazolam and propofol, in some case propofol was not used. Hemodynamic changes were minimal.
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