Chávez-Bravo NC, Palmerín-Bucio ME

Language: Spanish
References: 7
Page: 147-149
PDF size: 129.23 Kb.

ABSTRACT

The perineuroma is a rare benign tumor, derived from nerve sheath perineurial cells. It was first described in 1978 by Lazarus and Trombetta, who based their diagnosis on the ultrastructural features of perineurioma cells. Subsequently, the immunohistochemical profile of perineurial cells allowed an easier diagnosis of this condition. A case of perineurioma in a 47 year old woman is reported. The patient presented with an abdominal wall mass, with a previous diagnosis of malignant fibrous histiocytoma (MFH). The case was reviewed at an oncology hospital, inmunohistochemistry was performed and the concluding diagnosis was soft tissue perineurioma.

REFERENCES

1. Scheithauer BW, Woodruff JM, Erlandson RA. Atlas of pathology: tumors of the peripheral nervous system. 3rd Series, fascicle 24. Washington, DC: Armed Forces Institute of Pathology; 1997.

2. Hornick JL, Fletcher CD. Soft tissue perineurioma clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol 2005;29:845-858.

3. Emory TS, Scheithauer BW, Hirose T, Wood M, Onofrio BM, Jenkins RB. Intraneural perineurioma: a clonal neoplasm associated with abnormalities of chromosome 22. Am J Clin Pathol 1995;103:696-704.

4. Graadt van Roggen JF, McMenamin ME, Belchis DA, Nielsen GP, Rosenberg AE, Fletcher CD. Reticular perineurioma: a distinctive variant of soft tissue perineurioma. Am J Surg Pathol 2001;25:485-493.

5. Michal M. Extraneural retiform perineuriomas: a report of four cases. Pathol Res Pract 1999;195:759-763.

6. Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997;21:1433-1442.

7. Weiss SW, Goldblum JR. Enzinger and Weiss’s soft tissue tumors. Fourth edition. St. Louis, MO: Mosby; 2001. p. 111.