2009, Number 5
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Med Cutan Iber Lat Am 2009; 37 (5)
Imatinib-induced oral lichenoid eruption
Campos ML, Quesada CA, Feito RM, González-Obeso E, Casado JM, Vidaurrazaga Díaz-Arcaya C
Language: Spanish
References: 12
Page: 230-232
PDF size: 195.38 Kb.
ABSTRACT
Imatinib mesylate is a tyrosine kinase inhibitor. It is used to treat chronic myeloid leukaemia, dermatofibrosarcoma protuberans and gastrointestinal stromal tumours. Cutaneous reactions to imatinib are frequent and occur in 9’5-69% of patients, depending on the series reported. Maculopapular eruptions, generalized edema and periorbital edema are the most common adverse events observed. Lichenoid eruptions are very rare. We report a new case of imatinib-induced oral lichenoid eruption.
REFERENCES
Mauro MJ, Deininger MW. Chronic myeloid leukemia in 2006: a perspective. Haematologica 2006; 91: 152.
Savage DG, Antman KH. Imatinib mesylatea new oral targeted therapy. N Engl J Med 2002; 346: 683-93.
Matsuo E, Miyazaki Y, Tsutsumi C, Inoue Y, Yamasaki R, Hata T et al. Imatinib provides durable molecular and cytogenetic responses in a practical setting for both newly diagnosed and previously treated chronic myelogenous leucemia: a study in nagasaki prefecture, Japan. Int J Hematol 2007; 85: 132-9.
Robert C, Soria JC, Spatz A, le Cesne A, Malka D, Pautier P et al. Cutaneous sideeffects of kinase inhibitors and blocking antibodies. Lancet Oncol 2005; 6: 491-500.
Scheinfeld N. Imatinib mesylate and dermatology part 2: a review of the cutaneous side effects of imatinib mesylate. J Drugs Dermatol 2006; 5: 228-31.
Brazzelli V, Prestinari F, Roveda E, Barbagallo T, Bellani E, Vassallo C et al. Pityriasis rosea-like eruption during treatment with imatinib mesylate: description of 3 cases. J Am Acad Dermatol 2005; 53: S240-3.
Halevy S, Shai A. Lichenoid drug eruption. J Am Acad Dermatol 1990; 23: 689-93.
Roux C, Boisseau-Garsaud AM, Saint-Cyr I, Helenon R, Quist D, Delaunay C. Lichenoid cutaneous reaction to imatinib. Ann Dermatol Venereol 2004; 131: 571-3.
Lim DS, Muir J. Oral lichenoid reaction to imatinib (STI 571, Gleevec). Dermatology 2002; 205: 169-71.
Ena P, Chiarolini F, Siddi GM, Cossu A. Oral lichenoid eruption secondary to imatinib (Glivec). J Dermatolog Treat 2004; 15: 253-5.
Dalmau J, Peramiquel L, Puig L, Fernández-Figueras MT, Roe E, Alomar A. Imatinibassociated lichenoid eruption: acitretin treatment allows maintained anti neoplastic effect. Br J Dermatol 2006; 154: 1213-6.
Brouard M, Saurat JH. Cutaneous reactions to STI571. N Engl J Med 2001; 345: 618-9.