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ISSN 0210-5187 (Electronic)

2009, Number 5

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Med Cutan Iber Lat Am 2009; 37 (5)

Acquired zinc deficiency secondary to a synthetic diet

Rodríguez BAL, Jiménez PRJ, Galán GM, Vázquez BC, Vélez García-Nieto AJ, Moreno GJC

Language: Spanish
References: 15
Page: 213-216
PDF size: 280.75 Kb.


ABSTRACT

Acquired zinc deficiency is a syndrome definied for a triad: dermatitis, diarrhoea and alopecia plus low plasma zinc level. Dermatologic examination revealed vesicles, blisters and pustules predominantly in periorificial and acral regions. A rapid clinical response will occur, with complete healing of lesions due to administration of a zinc preparation.
A 20 years old woman, with typical skin lesions and low plasma zinc level, due to TPN (Total Parenterl Nutrition) in association with Crohn’s disease is reported. The knowledge of this syndrome and its diagnosis lead, through integrative therapy, to its resolution in a short time.


REFERENCES

  1. Danbolt N, Cross K. Acrodermatitis enteropathica. Acta Derm Venereol 1943; 23: 127-72.

  2. Moyahan EJ, Barnes PM. Zinc deficiency and a synthetic diet for a lactose intolerance. Lancet 1973; 676-7.

  3. Lucky AW. Cutaneous manifestations of endocrine, metabolic and nutritional disorders. En: Pediatric Dermatology de LA Schachner y RC Hansen eds. 1995: 1077-80.

  4. Thyresson N. Acrodermatitis enteropathica: report of a case healed with zinc therapy. Acta Derm Venerol 1974; 54: 383.

  5. Agget PJ, Harries JT. The current status of zinc in health and diseases states. Arch Dis Child 1979; 54: 909-17.

  6. Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr 1998; 68: 447-63.

  7. Michaelsson G, Ljunghall K. Patients with acne, psoriasis, dermatitis herpetiformis and Darier’s disease have low epidermal zinc concentrations. Acta Derm Venereol 1990; 70: 304.

  8. Bruske K, Safeld K. Zinc and its status in some dermatology diseases- a statistical assesment. Z Hautkr 1987; 62: 125.

  9. David TJ, Wells FE, Sharpe TC, Gibbs AC. Low serum zinc in children with atopic eczema. Br J Dermatolol 1984; 111: 597.

  10. Perafan-Riveros C, Franca LF, Alves AC, Sanches JA Jr. Acrodermatitis enteropathica: case report and review of the literature. Pediatr Dermatol 2002; 19: 426-31.

  11. Freedberg IM, Eisen AZ, Austen KF, Goldsmith LA, Katz SI, Fitpatrick TB. Acrodermatitis enteropática y otros trastornos por déficit de zinc. Fitzpatrick. En: Dermatología en Medicina General, de: TB Fitzpatrick. Buenos Aires (Argentina). 5ª edición 2001; 1834-40.

  12. Weismann K, Hoe S, Knudsen L, Sorensen SS. Zinc absortion in patients suffering from acrodermatitis enteropathica and in normal adults assesed by wholebody counting technique. Br J Dermatol 1979; 101: 573-9.

  13. Mancini J, Tunnessen WW. Acrodermatitis enteropathica like rash in a breast-fed full term infant with zinc deficiency. Arch Pediatr Adolesc Med 1998; 152: 1239-40.

  14. Odeh M. The role of zinc in acquired immunodeficiency syndrome. J Intern Med 1992; 231: 463-9.

  15. Coello-Ramírez P. Acrodermatitis enteropathic treated with zinc sulfate. Report of a case. Bol Med Hosp Infant Mex 1977; 34: 331-9.




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