Martínez SA, Cisneros MI, González VD, Arriaga DC, Morilla GA

Language: English/Spanish
References: 22
Page: 123-127
PDF size: 356.33 Kb.

ABSTRACT

Classical swine fever virus (CSFV) infection depletes all circulating leukocyte subpopulations and induces immunosuppression in pigs that get infected and die. However, there are no reports on the effect of leukocyte concentrations in animals that survive the viral infection. In order to determine this effect, six pigs of 45 days of age, that developed the disease and survived during an experimental infection, were used. Parameters evaluated included: Clinical signs, rectal temperature, haematic biometry and lymphocyte subpopulations measured by rosettes with erythrocytes. Results showed that rectal temperature increased from day seven until day twelve after the infection. The latter was associated with lack of appetite, weakness and slight diarrhea. Concentration of leukocytes, lymphocytes, segmented and banded polymorphonuclear cells, monocytes, T total (TE), T high affnity (Taa), B with fc receptor (Bfc) and Null lymphocyte subpopulations was decreased during the first seven days. Concentration of autologous T (Taut) lymphocytes, which are immature cells at the same time, was increased, and there was no alteration on the concentration of B lymphocytes with the complement receptor (Bc). Moreover, concentration of most of the cells starting the seventh day on after the infection was increased, but Taut was decreased. These results indicate that the recovery of the disease was associated with an increase in almost all leukocyte and lymphocyte subpopulations.

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