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1994, Number 4

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Vet Mex 1994; 25 (4)

Generalized nodular dermatofibrosis and bilateral renal cystadenocarcinoma. A case report

Aburto FE, Gómez DE, Paredes PJ, Sánchez LR

Language: English/Spanish
References: 13
Page: 357-361
PDF size: 4817.03 Kb.


Text Extraction

A clinical and morphological description of a general nodular dermatofibrosis, associated to bilateral renal cystadenocarcinoma, is described. This case was found in a 10 year old Belgian Shepherd crossbred bitch. The animal presented multiple firm cutaneous nodules composed of dense well differentiated collagen tissue in the head and forelimbs. This problem had started five years ago. The presence of cystic tumors in both kidneys with metastases to the liver, peritoneal surfaces, regional lymph nodes, spleen, adrenal glands and lungs were also detected. Cited literature was consulted and therefore, the possible associations of the lesions, the pathogeny and the relation with other comparable syndromes in human beings to this case, are discussed.


REFERENCES

  1. Baskin, G.B. and Paoli de, A.: Primary renal neoplasms of the dog. Vet. Pathol., 14: 591-605 (1977).

  2. Cosenza, S.F. and Seely, J.C.: Generalized nodular dermatofibrosis and renal cystadenocarcinoma in a German Shepherd dog. J. Am. vet. med. Ass., 189: 443-452 (1986).

  3. Cotran, R.D., Kumar, V. y Robbins, S.L.: Patología Estructural y Funcional. 4a ed. Interamericana-McGraw-Hill, Madrid, España, 1990.

  4. Fox, J.G., Snyder, S.B. and Campbell, C.H.: Connective tissue nevus in a dog. Vet. Pathol., 10: 65-68 (1973).

  5. Gilbert, P.A., Griffin, C.E. and Walder, E.J.: Nodular dermatofibrosis and renal cystadenoma in a German Shepherd dog. J. Am. Anim. Hosp. Ass., 26: 253-256 (1990).

  6. Klein, M.K., Cockerell, G.L., Harris, C.K., Withrow, S.J., Lulich, J.P., Ogilvie, G.K., Norris, A.M., Harvey, H.J., Richardson, R.F., Fowler, J.D., Tomlinson, J. and Henderson, R.A.: Canine primary renal neoplasms: A retrospective review of 54 cases. J. Am. Anim. Hosp. Ass., 24: 443-452 (1988).

  7. Lium, B. and Moe, L.: Hereditary, multifocal renal cystadenocarcinomas and nodular dermatofibrosis in the German Shepherd dog: Macroscopic and histopathologic changes. Vet. Pathol., 22: 447-455 (1985).

  8. Roberts, A.B., Frolik, C.A., Azano, M.A. and Sporn, M.B.: Transforming growth factors from neoplastic and non neoplastic tissues. Fed. Proc., 42: 2621-2626 (1983).

  9. Rubin, E. y Farber, J.L.: Patología. Editorial Médica Panamericana, México, D.F., 1990.

  10. Scott, D.W., Yager, J.A., Manning, T.O., Walton, D.K., Johnson, R.P., Parker, W.M. and Carman, P.S.: Nevi in the dog. J. Am. Anim. Hosp. Ass., 20: 505-512 (1984).

  11. Sutter, M., Lott-Stolz, G. and Wild, P.: Generalized nodular dermatofibrosis in six Alsatians. Vet. Pathol., 20: 632-634 (1983).

  12. Uitto, J., Bauer, E.A. and Santa-Cruz, D.J.: Decreased collagenase production by regional fibroblast cultured from skin of a patient with connective tissue nevi of the collagen type. J. Invest. Dermatol., 78: 136-140 (1982).

  13. Uitto, J., Santa-Cruz, D.J. and Eisen, A.Z.: Familial cutaneous collagenoma: Genetic studies on a family. Br. J. Dermatol., 101: 185-195 (1979).




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