Sterility in the dog induced by injection of methylcyanoacrylate into the tail of the epididymis

M del R Esperanza Galván Pérez; Rosa Ma Páramo Ramírez; Carlos Esquivel Lacroix; Javier Valencia Méndez

1994, Number 3

<< Back Next >>

Vet Mex 1994; 25 (3)

Sterility in the dog induced by injection of methylcyanoacrylate into the tail of the epididymis

Galván PMRE, Páramo RRM, Esquivel LC, Valencia MJ

Full text

How to cite this article

Language: English/Spanish
References: 21
Page: 261-265
PDF size: 469.17 Kb.

ABSTRACT

The aim of this study was to induce azoospermia in the dogwith the injection of methylcyanoacrilate (MCA) in the tail of the epididymis. MCA was injected in the tail of both epididymis of 15 medium and small size dogs. Two other dogs were injected with distilled water as the control group. Sperm were collected and evaluated prior to the treatment, 15 and 30 days after the treatment, and every other month till day 180. Nine dogs were azoospermic 15 days after the treatment and 13 (86.7%) by day 30^th. After 180 days, one dog still had sperms in the ejaculate, with high proportion of dead (40%) and abnormal ones (60%). Histological examination of the testis in the dogs injected with MCA showed a difuse interstitial fibrosis, with mononuclear cell infiltration and necrosis. In the control animals no significant changes ocurred. The injection of MCA in the epididymal tail in dogs is a cheap, quick, simple and practical method, that could be used in massive sterilization programmes to control their overpopulation.

REFERENCES

Allen, E.W.: Infertility in the dog. In Pract., 7: 161-166 (1975).
Anonymous: National Conference on Dog and Cat Control: Summary and Conclusion. J. Am. vet. med. Ass., 168: 1125-1134 (1976).
Barnett, B.D.: Chemical vasectomy of domestic dogs in the Galapagos Islands. Theriogenology, 23: 499-509 (1985).
Cofram, P.A., Richard, R.M. and Taylor, H.C.: Response of the rabbit oviduct to a tissue adhesive. Science, 148: 1348-1350 (1965).
Díaz, E., Valencia, J . y Aluja, Aline S. de: Esterilidad en el perro inducida por la inyección de formaldehido en la cola del epidídimo. Vet. Méx., 12: 73-80 (1981).
Flores, C.R., Uruchurtu, M.A., Ruiz, S.H. y Ordóñez, M.L.: Un estudio de 50 necropsias en perros callejeros. Vet. Méx., 8: 131-139 (1977).
Freeman, C. and Doffey, D.S.: Sterility in male animals induced by injection of chemical agents into the vas deferens. Fertil. Steril., 24: 884-890 (1973).
Fuentes, M.R., Cárdenas, L.J. y Aluja, Aline S. de: Cálculo de la población canina en la ciudad de México, determinación de sus condiciones de atención y destino. Vet. Méx., 12: 59-71 (1981).
Neuwirth, R.S., Richart, R.M. and Taylor, H.C.: Chemical induction of tubal blockade in the monkey. Obstet. Gynecol., 38: 51-54 (1971).
Neuwirth, R.S., Richart, R.M., Stevenson, T., Bolduc, R.L., Zinser, H., Baur, H., Cohen, J., Eldering, G., Rivas, G.A. and Nilsen, PA.: An outpatient approach to female sterilization with methyl cyanoacrylate. Am. J. Obstet. Gynecol., 136: 951-956 (1980).
Ohio Veterinary Medical Association: Uncontrolled and unwanted pets: A major public problem. Vet. Med. Small Anim. Clin., 72: 1705-1711 (1977).
Pineda, M.H. and Hepler, D.L.: Chemical vasectomy in dogs. Theriogenology, 16: 1-11 (1981).
Pineda, M.H., Reimers, T.V., Faulkner, L.C., Hopwood, M.L. and Seidel, G.E.: Azoospermia in dogs induced by injection of sclerosing agents into the cauda of the epididymidis. Am. J. vet. Res., 38: 831-838 (1977).
Rangel, F., Cárdenas, L. and Aluja, Aline S. de: The canine population of Mexico City. Anim. Regul. Stud., 4: 281-289 (1981).
Schenker, J.G. and Polishuk, W.Z.: The effect of tissue adhesive on the endometrium of the rabbit. Contraception, 7: 145-152 (1973).
Schnaas, G. y Román, G.: Estudio sobre la población canina en México. Gac. Med. Méx., 92: 508-513 (1962).
Schneider, R.: Observation on overpopulation of dogs and cats: Demographic aspects. J. Am. vet. med. Ass., 167: 281-284 (1975).
Segoviano, C.S.: Efecto de las sales de cadmio en el testículo del perro. Vet. Méx., 6: 21-27 (1975).
Stevenson, T.C.: The effect of methyl cyanoacrylate tissue adhesive on the human Fallopian tube and endometrium. J. Obstet. Gynecol., 79: 1028-1032 (1972).
Wildt, E.D., Seager, W.J. and Bridges, H.Ch.: Sterilization of the male dog and cat by laparoscopic occlusion of the ductus deferens. Am. J. vet. Res., 42: 1888-1897 (1981).
Zestel, N.: Controlling pet population. J. Am. vet. med. Ass., 167 (Abstr.): 236 (1975).