2001, Number 2
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Alerg Asma Inmunol Pediatr 2001; 10 (2)
Smoking and allergy development in childhood.
Rojas GA, López PG, Orozco MS, Guerrero SE, Huerta LJG
Language: Spanish
References: 24
Page: 43-52
PDF size: 472.19 Kb.
ABSTRACT
Breathing other people’s smoke is called passive, involuntary or second-hand smoking. Environmental tobacco smoke is a major source of indoor air pollution to which many children are exposed. A number of carcinogens and other harmful compounds have been identified in tobacco. Maternal smoking, particularly in utero, is clearly associated with an increased risk for the later development of childhood atopy and asthma. It’s estimated that children from smoking households have twice the risk of developing asthma. Moreover, passive smoking is causally associated with an increased risk of ear and sinus infections and lower respiratory tract infections such as pneumonia and bronchiolitis. Passive smoking causes a reduction in lung function and increased severity in the symptoms of asthma in children, and produces many long-term complications such as cardiovascular disease and cancers due to tobacco use. Smoking is known to increase the inflammatory burden of the lower respiratory tract through a number of related but separate mechanisms. These include the recruitment of increased numbers of inflammatory cells, alteration in cell subtypes, enhancement of some cellular functions and proinflammatory mediator release. In addition, greater effort must be spent on smoking cessation.
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