Mejía-Covarrubias F, López-López JR, Sernas-Romero N, López-Pérez G

Language: Spanish
References: 16
Page: 158-164
PDF size: 377.89 Kb.

ABSTRACT

Objective: To establish the relation between the familiar antecedent of atopic disease, characteristics of feeding, frequency of exhibition towards environmental allergens and the allergic diseases in patients taken care of in the unit of Pediatria of the General Hospital of Mexico. To identity the main agents that caused by prick skin them tests.
Material and methods: 535 clinical files of patients were reviewed, they were grouped according to familiar sex, age, antecedent of atopic disease, autoimmunity and immunodeficiency; the age of ablactation was classified in early (0 to 3 months), adapted of 4 to 6 months and delayed of 7 months, and the types of used foods were evaluated too. It was taken into account the diagnosis as well as the results from the prick skin tests. Finally, the environmental factors in each patient were taken into account: dust, humidity, coexistence with animals, smoking, environmental pollution and contact with flowers.
Results: They were 58% males and females 42%. 30% were smaller of 6 years old, 45% of 6 to 10 years old and 24% of 11 to 15 years old. 30.8% with antecedent of atopic disease of first degree and 27.6% of second degree. 48% received breast feeding during less than 3 months. Early ablactation was done in 62%. Cutaneous tests were positives to 849 allergens, 280 existed towards dust mites. 38 cases were of rhinitis, 7 of atopic dermatitis, 277 of rhinosinusitis, 117 of asthma, 21 of bronchial hyperreactivity, 58 of sinusitis, 6 of allergic conjunctivitis and 11 existed of prolonged infection.
Conclusions: In this group the allergic disease is of multifactorial etiologic, the familiar antecedent of atopia is determining, the early ablactation and brevity of breast feeding also conditions it, the main allergen is the dust mites and finally the rhinosinusitis predominates in this group.

REFERENCES

1. Philip F. Otitis media and eustachian tube dysfunction: Connection to allergic rhinitis. J Allergy Clin Immunol 1997; 99: S787-S797.

2. Orozco-Martínez S, López-Pérez G, Peña-Echeverry N, Arreguín-Osuna L, Huerta-López J. Frecuencia de atopia familiar, alimentación al seno materno y edad de ablactación en pacientes con asma, rinitis alérgica o urticaria. Alergia, Asma e Immunol Pediatr 1996; 5: 9-14.

3. Naranjo-Estrella J, Ocaña-Amores R, Field-Cortazares J, Sánchez-Ojeda M, Del Río-Navarro B, Sienra-Monge JJ. Perfil clínico del asma en niños y factores asociados, en pacientes del Hospital Infantil de México. Alergia, Asma e Inmunol Pediatr 1998; 7: 176-179.

4. Rodney IE, Diane Du Toit. Risk Factors for childhood asthma and wheezing. Importancy of maternal and household smoking. Am J Respir Crit Care Med 1996; 154: 681-688.

5. Wahn U, Lau S. Indoor allergen exposure is a risk factor sensitization during the firs three years of life. J Allergy Clin Immunol 1997; 99: 763-769.

6. Kuehr J, Frischer T. Mite allergen exposure is a risk for the incidence of specific sensitization. J Allergy Clin Immunol 1994; 94: 44-52.

7. Peat PK, Tovey E. House Dust Mite allergens. A major risk factor For childhood sthma in Australia. Am J Respir Crit Care Med 1996; 153: 141-146.

8. Sampson BS. Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma. J Allergy Clin Immunol 1996; 97: 1993-401.

9. Leung R. Sensitization to inhaled allergens as a risk factor for asthma an allergic disease in Chinese population. J Allergy Clin Immunol 1997; 99: 594-599.

10. Squillace SP, Sporik RB. Sensitization to dust mites as a dominant risk factor for asthma among adolescents living in a Central Virginia. Am J Respir Crit Care 1997; 156: 1760-1764.

11. Lieu TA. Outpatient management practices associated with reduced risk of pediatric asthma hospitalization and emergency department visits. Pediatrics 1997; 100: 334-341.

12. Tariq SMI. The prevalence of and risk factors for atopy in early childhood: A whole population birth cohort study. J Allergy Clin Immunol 1998; 101: 587-593.

13. Sasai K. Early detection of specific IgE antibody against house dust mite in children at risk of allergic disease. J Pediatr 1996; 128: 834-840.

14. Siersted HC, Boldsen J. Population based study of risk factors for underdiagnosis of asthma in adolescence: Odense schoolchild study. Brit Med J 1998; 316: 651-656.

15. Kajosaari M. Atopy prevention in chilhood: the role of diet prospective 5-year follow-up of high-risk infants with six months exclusive breast feeding and solid food elimination. Pediatr Allergy Immunol 1994; 5:26-28.

16. Ortiz-Aldana I, Arreguín-Osuna L, Cerino-Javier R, Meza-Morales A. Factores de riesgo para el desarrollo de enfermedades atópicas. Alergia e Inmunol Pediatr 1995; 4: 150-152.