medigraphic.com
ISSN 2007-8560 (Print)
Órgano Oficial de Difusión Científica de la Federación Mexicana de Colegios de Ortopedia y Traumatología, A.C. (FEMECOT)

2009, Number 4

<< Back Next >>

Ortho-tips 2009; 5 (4)

Factores de crecimiento derivados de plaquetas en el trasplante de menisco: trabajo experimental en borregos

Berumen NE, Morales TC, Paz M, Campbell O, Leal BI

Language: Spanish
References: 30
Page: 315-325
PDF size: 0. Kb.


ABSTRACT

Introduction: A comparative study was carried out in Peliguey rams knees to determine the effects of Autologous Growth Factors (AGF) in meniscal transplantation surgery. Material and methods: Eight rams were meniscectomized, four of them had a meniscus transplantation with addition of AGF, the other four just had the transplantation without the AGF and were keepet as control group. All of them had a check up at two and four months after the meniscus transplant. All the meniscus size were messured and an histological analysis was done in order to determine possible cell migration and new blood vessels growing. Results: In Group 1 an increase of the inflammatory reaction in the joint between the capsule and the meniscus was noticed, there was not a cellular restocking inward the allograft. Instead the Group 2 (AGF) was found with a lower inflammatory reaction, a cellular restocking inwards the allograft and growing of new blood vessels close to its edge were observed. A minor shrinkage of the transplanted meniscus was detected in this group compared with the meniscus size of the control group. Discussion: For first time AGF was applied to a meniscus transplantation and a significant difference was observed between the control and those in which AGF were applied. Conclusions: The AGF application in meniscus transplantation is a tool to improve the integration of the implant.


REFERENCES

  1. Greis PE, Bardana DD, Holmstrom CM, Burks TR. Meniscal Injury: I. Basic Science and Evaluation. J Am Acad Orthop Surg May 2002; 10: 168-76.

  2. Dehaven EK, Arnoczky SP. Meniscal repair: part I: basic science, indications for meniscal repair: part I: basic science, repair, and open repair. J Bone Joint Surg Am 1994; 76: 140-52.

  3. Allen PR, Denham RA, Swan AV. Late degenerative changes after meniscectomy. Factors affecting the knee after operation. J Bone Joint Surg Br 1984; 66: 666-71.

  4. Bourne RB, Finlay JB, Papadopoulos P, Andreae P. The effect of medial meniscectomy on strain distribution in the proximal part of the tibia. J Bone Joint Surg Am 1984; 66: 1431-7.

  5. Indelli P, Vestri R, Szivek J, Schnepp A, Andrew S, Grana W. Distribución de las cargas en los cóndilos femorales de la rodilla: Estudio biomecánico en perros. Rev Argent Artrosc 2004; 11(1): 54-8.

  6. Tapper EM, Hoover NW. Late results after meniscectomy. JBJS 82A 80-8; 2000.

  7. Larson RL. Editorial. The Knee-the physiological joint. JBJS 1983; 65A: 143-144.

  8. Fairbank TJ. Knee joint changes alter meniscectomy. JBJS 1948; 30: 664-70.

  9. Kurosawa H, Fukubayashi T, Nakajima H. Load-bearing mode of the knee joint: Physical behavior of the knee joint with or without menisci. Clin Orthop 1980; 149: 283-290.

  10. Arnoczky SP, Warren RF. Microvasculature of the human meniscus. Am J Sports Med 1982; 10(2): 90-5.

  11. Henning CE, Lynch MA Clark JR. Vascularity for healing of meniscus repairs. Arthroscopy 1987; 3: 13-18.

  12. Greis PE, Holmstrom CM, Bardana DD, Burks RT. Meniscal Injury: II. Management. J Am Acad Ortho Surg 2002; 10: 177-87.

  13. Pavlovich RI. Hi-frequency electrical cautery stimulation in the treatment of displaced meniscal tears. Arthroscopy 1998; 14(6): 566-71.

  14. Milachowski KA, Weismeier K, Wirth CJ. Homologous meniscus transplantation: Experimental and clinical results. Int Orthop 1989; 13: 1-11.

  15. Rodeo SA, Seneviratne A, Suzuki K, Felker K, Wickiewicz TL, Warren RF. Histological analysis of the human meniscal allografts. A preliminary report. JBJS. Am 82: 1071-1082, 2000.

  16. Shelton WR, Tracy SH, Dukes AD, et al. Use of allografts in the knee reconstruction II, Surgical considerations. J Am Acad Orthop Surg 1998; 6: 169-175.

  17. Stollsteimer GT, Shelton WR, Dukes A, Bomboy AL. Meniscal allograft transplantation; a 1 to 5 years follow-up of 22 patients. Arthroscopy 2000; 16: 343-7.

  18. Verstraete KL, Verdon KR, Lootens T. et al. Current status and imaging of allograft meniscal transplantation. Eur J Radiol 1997; 26: 16-22.

  19. Berumen E. Una historia que vale la pena contarse. Acta Ortopédica Mexicana 2002; 16(4): 241.

  20. Berumen NE, Chung AD, Lozano PJ, Iñigo PR, Álvarez E, Regla H, Busto VJM, Ochoa RE, Morales TC. Trasplante de Menisco; experiencia en México, Grupo de Estudio Del Colegio Mexicano de Cirujanos Artroscopistas y Cirujanos de Rodilla (COMACIR), en publicación.

  21. Campbell COA, De la Riva I, Vallejo PJ, Aguirre MA, Berumen NE. Trasplante de menisco. Resultado clínico en pacientes con trasplante de menisco usando la técnica de doble túnel artroscópica pura sin taquetes óseos. Revista Latinoamericana Artroscopía y Traumatología del Deporte 2004; 01: 26-34.

  22. Jackson DW, Whelan J, Simon TM. Cell survival after transplantation of flesh meniscal allografts. DNA probe analysis in a goat model. Am J Sports Med 1993; 21: 540-50.

  23. Noyes FR, Barber WSD, Butler DL, et al. The role of allografts in repair and reconstruction of knee joint ligaments and menisci. Instr Cours Lect 1998; 47: 379-96.

  24. Puierce GF, Mustoe TA, et al. Platelet derived growth factor and transforming growth factor beta enhance tissue repair by unique mechanisms. J Cell Biol 1989; 109: 439.

  25. Matras H. Die Wirkungen verschiedner. Fibrin praparatte auf konstinuitat-strennungen ratten-haut. Osterr Z Starat 1970; 67: 338.

  26. Hood AG, Hill AG, et al. Perioperative autologous sequestration III. A new physiologic glue with wound healing properties. Am Acad Cardiovascular Perfussion 1993; 14: 126.

  27. PRGF System: técnica de obtención de plasma rico en factores de crecimiento. http://www.gacetadental.com/marzo2001/productos/12.htm

  28. Verdonk R, Almqvist FK, Huysse W, Verdonk CP. Meniscal Allografts: Indications and outcomes. Sports Med Arthrosc Rev 2007;15: 121-5.

  29. Cummins JF, Mansour JN, Howe Z, Allan DG. Meniscal transplantation and degenerative articular change: an experimental study in the rabbit. Arthroscopy 1997; 13: 485-91.

  30. Szomor ZL, Martin TE, Bonar F, Murrell GA. The protective effects of meniscal transplantation on cartilage: an experimental study in sheep. J Bone Joint Surg Am 2000; 82: 80-8.




2020     |     www.medigraphic.com