Hernández JP, Rivas SF

Language: English/Spanish
References: 4
Page: 45-50
PDF size: 1805.34 Kb.

ABSTRACT

With the aim to evaluate the early inflammatory changes of the intestinal mucosa and submucosa after the attachment of Ancylostoma caninum in the small bowel, a model of a vascular marker was used by means of the injection of India ink at 50% in saline solution in the mesenteric artery. This artery irrigates a territory of the intestine where the adult nematodes were previously placed 60 minutes before. A group of naturally infected dogs and other dogs without parasites were also studied using the same methodology. India ink particles were predomionantly found in the small blood vessels of the submucosa with a range of 5 mm next to the parasite attachment. The vascular response was evident with dilatation and congestion of the blood vessels, diapedesis of erythrocytes and polymorphonuclear leucocytes. Plasmatic proteins and carbon particles leaked from the vascular lumen by gaps in the endothelial cells. The fenestra appeared normal and it did not apparently participate in the active leakage. Natural attachment of the parasites was also characterized by acute vascular changes and a chronic inflammatory cell response. Hipoproteinemia and anemic processes, after ancylostomiasis parasitism, may be explained in terms of the continuously fluid of the protein extravasation and protein ingestion by the parasites.

REFERENCES

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