Landeros-Navarro IY, Vilma Zepeda-López V

Language: Spanish
References: 20
Page: 150-155
PDF size: 61.90 Kb.

ABSTRACT

Introduction: Dexmedetomidine has sedative, hypnotic, analgesic, and sympatholytic properties. It also decreases the release of catecholamines and diminishes opiate requirement and inhaled analgesics. The patient’s well-being during the surgical intervention includes a proper sedation. Our objective in this study consists of comparing the differences in dexmedetomidine sedation effects with and without impregnation in patients under regional anesthesia. Methodology: The study used 2 groups of 30 patients each under regional anesthesia. Group A: Impregnation of 0.5 µg/kg for 20 minutes before the surgery and maintenance of 0.3 µg/kg/hour. Group B: Infusion of 0.3 µg/kg/hour. The following parameters were evaluated: sedation level (Ramsay) mean arterial pressure, cardiac frequency, arterial oxygen saturation every 5 minutes during the transoperative period. Results: Anxiolysis is similar when using dexmedetomidine with and without impregnation (p 0.712). The observed side effects were hypotension and bradycardia. There was no significant difference between both groups with regard to mean arterial pressure (p 0.256), cardiac frequency (p 0.407), arterial oxygen saturation (p 0.581). These findings were similar to other researches. Conclusion: Dexmedetomidine given with and without impregnation produces similar sedation. The incidence of side effects with both administration techniques is similar.

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