Reddy P, Ramana DCV, Vidyullatha V, Prasad MH, Reddy PP

Language: English
References: 18
Page: 87-90
PDF size: 24.52 Kb.

ABSTRACT

Introduction. The incidence of chromosomal aberrations was evaluated in mint factory smokers workers exposed to metal alloys of aluminium, copper, nickel and magnesium.
Material and methods. Heparinised blood samples were collected from 50 smokers exposed to metallic dust and fumes, 28 non smokers and 30 smokers who were not exposed to metallic dusts and fumes (belonging to same socioeconomic group as that of workers). All the samples were analysed for the incidence of chromosomal aberrations. Further, the total exposed population were categorised into 4 groups based on the duration of exposure.
Results. There was a significant increase of chromosomal aberrations in the smoker exposed to metal alloys when compared to the controls. An increase of chromosomal gaps, breaks, fragments, deletions was observed, as the duration of the exposure to metal dust is increased.
Discussion. Our study warrants that undue exposure of man to these metals in industrias might result in genetic damage and hence appropriate precautionary measures have to be taken by workers to minimise exposure in their work environment.

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