medigraphic.com

2009, Number 2

<< Back Next >>

Vet Mex 2009; 40 (2)

Incidence of uterine pathologies and fertility of Holstein cows treated with selenium and vitamin E before and after parturition

Ruiz JLA, Aréchiga FCF, Morales RS, Ortiz GO, Gutiérrez CG, Hernández CJ

Language: English/Spanish
References: 46
Page: 133-140
PDF size: 166.46 Kb.


ABSTRACT

An antioxidant therapy based on vitamin E and selenium subcutaneous (sc) injections administered prior to and after parturition, was evaluated by measuring the incidence of uterine pathologies and fertility in lactating Holstein cows. Cows (n = 353) were randomly distributed into three groups: Group pre-postpartum (n = 122), cows received a sc injection of 50 mg Se and 680 IU vitamin E (10 mL of Mu-Se) on 60 and 21 days prepartum and 30 and 90 days postpartum; Group prepartum (n = 117) received a sc injection 21 days prior to parturition; control Group (n = 114), cows received sc injections of saline solution (SS, 10 mL) on 60 and 21 days prepartum and 30 and 90 days postpartum. Incidence of retained fetal membranes (RFM) in control Group (20.1%) was similar (P › 0.05) to prepartum Group (12.8%), but it differed (P ‹ 0.05) from pre-postpartum Group (6.5%). The percentage of cows with haemorrhagic metritis (HM) was similar among groups (8.7%; P › 0.05). Proportion of cows with purulent metritis (PM) in control Group (37.7%) was similar (P › 0.05) to prepartum Group (33.3%), but reduced (P ‹ 0.05) in pre-postpartum Group (23.7%). The global proportion of cows showing any of the evaluated pathologies was similar (P › 0.05) for control groups (44.7%) and prepartum Group (40.1%) but lower (P ‹ 0.05) for pre-postpartum Group (27%). Pregnancy rate at 150 days postpartum (PP) was greater (P ‹ 0.08) for pre-postpartum Group (70%) than control Group (58.9%). In conclusion, an antioxidant therapy based on vitamin E and selenium administration, 60 and 21 days prior to parturition and 30 and 90 days after parturition, reduces the incidence of uterine pathologies and improves pregnancy rate at 150 days postpartum in Holstein cows.


REFERENCES

  1. LOPACZYNSKI W, ZEISEL SH. Antioxidants, programmed cell death, and cancer. Nutr Res 2001;21:295-307.

  2. BERRY EM, KOHEN R. Is the biological antioxidant system integrated and regulated? Med Hypotheses 1999;53:397-401.

  3. BURK RF, HILL KE. Regulation of selenoproteins. Annu Rev Nutr 1993;13:65-81.

  4. MACPHERSON A. Selenium, vitamin E and biological oxidation. In: GARNSOWORTHY PC, COLE DJA, editors. Recent Advances in Animal Nutrition. Nottingham UK: Nottingham University Press, 1994:3-30.

  5. WANG X, QUINN PJ. The location and function of vitamin E in membranes (review). Mol Membr Biol 2000; 17:143-156.

  6. YOUNG FM, LUDERER WB, RODGER RJ. The antioxidant β-carotene prevents covalent cross-linking between cholesterol side-chain cleavage cytochrome P450 and its electron donor, adrenodoxin, in bovine luteal cells. Mol Cell Endocrinol 1995;109:113-118.

  7. SEGERSON EC JR, MURRAY FA, MOXON AL, REDMAN DR, CONRAD HR. Selenium/vitamin E: role in fertilization of bovine ova. J Dairy Sci 1977; 60:1001-1005.

  8. FUJITANI Y, KASAI K, OHTANI S, NISHIMURA K, YAMADA M, UTSUMI K. Effect of oxygen concentration and free radicals on in vitro development of in vitro produced bovine embryos. J Anim Sci 1997; 75:483.

  9. MARTÍN CASTAÑEDA G. Efecto de la aplicación subcutánea de vitamina E y selenio en vacas Holstein superovuladas sobre el desarrollo y la calidad de los embriones recolectados vía transcervical (tesis de maestría). Zacatecas (Zacatecas) México: Universidad Autónoma de Zacatecas, 2005.

  10. HARRISON JH, HANCOCK DD, CONRAD HR. Vitamin E and selenium for reproduction of the dairy cow. J Dairy Sci 1984; 67:123-132.

  11. ARECHIGA CF, ORTIZ O, HANSEN PJ. Effect of prepartum injection of vitamin E and selenium on postpartum reproductive function of dairy cattle. Theriogenology 1994; 41:1251-1258.

  12. ARECHIGA CF, VAZQUEZ-FLORES S, ORTIZ O, HERNANDEZ CJ, PORRAS A, MCDOWELL LR et al. Effect or injection of β-carotene or vitamin E and selenium on fertility of lactating dairy cows. Theriogenology 1998; 50:65-76.

  13. SCHINGOETHE DJ, KIRKBRIDE CA, PALMER IS, OWENS MJ, TUCKER L. Response of cows consuming adequate selenium to vitamin E and selenium supplementation prepartum. J Dairy Sci 1982; 65:2338-2344

  14. ISHAK MA, LARSON LL, OWEN FG, LOWRY WR, ERICKSON ED. Effects of selenium, vitamins, and ration fibre on placental retention and performance of dairy cattle. J Dairy Sci 1983; 66:99-106

  15. PAULA-LOPES FF, AL-KATANANI YM, MAJEWSKI AC, MCDOWELL LR, HANSEN PJ. Manipulation of antioxidant status fails to improve fertility of lactating cows or survival of heat-shocked embryos. J. Dairy Sci 86:2343–2351

  16. ALLISON RD, LAVEN RA. Effect of vitamin E supplementation on the health and fertility of dairy cows: a review. Vet Rec 2000; 147:703-708.

  17. ROSILES MR, AGUILAR AMA, RAMÍREZ LJ. Deficiencia de selenio en un hato de bovinos que sufren del síndrome de mal de altura de Ixtlahuaca, Estado de México. Vet Méx 1997; 28:55-57.

  18. GARCÍA E. Modificación al sistema de clasificación climática de Köpen. 4ª ed. México DF: Instituto de Geografía-UNAM, 1987.

  19. NATIONAL RESEARCH COUNCIL. Nutrient Requirements of dairy cattle. Washington DC: National Academy Press, 2001.

  20. ZEMJANIS R. Reproducción animal: diagnóstico y técnicas terapéuticas. México DF: Ed. Limusa, 1975.

  21. STATISTICAL ANALYSIS SYSTEM. In: SAS/STATTM user’s guide. Release 6.03. Cary, NC: SAS Institute Inc., 1988.

  22. EILER H. Retained placenta. In: YOUNGQUIST RS, editor. Current Therapy in Large Animal Theriogenology. Philadelphia USA: WB Saunders Company, 1997:340-348.

  23. JULIEN WE, CONRAD HR. Selenium and vitamin E and incidence of retained placenta in parturient dairy cows. J Dairy Sci 1976; 59:1954-1959.

  24. MILLER JK, BRZEZINSKA-SLEBODZINSKA E, MADSEN FC. Oxidative stress, antioxidants, and animal function. J Dairy Sci 1993; 76:2812-2823.

  25. KANKOFER M. Non-enzymatic antioxidative defense mechanisms against reactive oxygen species in bovineretained and not-retained placenta: vitamin C and glutatione. Reprod Dom Anim 2001; 36:203-206.

  26. KANKOFER M. Antioxidative defense mechanisms in bovine placenta and their importance for placental release. Reprod Dom Anim 2000; 35:229-233.

  27. BRZEZIÑSKA-SLEBODZINSKA E, MILLER JK, QUIGLEY JD, MOORE JR. Antioxidant status of dairy cows supplemented prepartum with vitamin E and selenium. J Dairy Sci 1994; 77:3087-3095.

  28. EICHER SD, MORRILL JL, BLECHA F. Vitamin concentration and function of leukocytes from dairy calves supplemented with vitamin A, vitamin E, and β-carotene in vitro. J Dairy Sci 1994; 77:560-565.

  29. NDIWENI N, FINCH JM. Effects of in vitro supplementation with α-tocopherol and selenium on bovine neutrophil functions: implications for resistance to mastitis. Vet Immunol Immunopathol 1996; 51:67-78.

  30. HEUWIESER W, GRUNERT E. Significance of chemotactic activity for placental expulsion in cattle. Theriogenology 1987; 27:907-912.

  31. GILBERT RO, GRÖHN YT, GUARD CL, SURMAN V. Impaired post-partum neutrophil function in cows which retain fetal membranes. Res Vet 1993; 55:15-19.

  32. GRÖHN YT, ERB HN, MCCULLOCH CE, SALONIEMI HS. Epidemiology of reproductive disorders in dairy cattle: associations among host characteristics, disease and production. Prev Vet Med 1990; 8:25-39.

  33. POLITIS I, HIDIROGLOU M, BATRA TR, GILMORE JA, GOREWIT RC, SCHERF H. Effects of vitamin E on immune function of dairy cows. Am J Vet Res 1995; 56:179-184.

  34. NOCKELS C. Antioxidants improve cattle immunity following stress. Anim Feed Sci Technol 1996; 62:59-68.

  35. ZAVY MT. Embryonic mortality in cattle. In: ZAVY MT, GEISERT RD, editors. Embryonic mortality in domestic species. Boca Raton Florida: CRC Press, 1994:99-140.

  36. SEGERSON EC, LIBBY DW. Ova fertilization and sperm number per fertilized ovum for selenium and vitamin E-treated Charolais cattle. Theriogenology 1982; 17:333-341.

  37. GARDINER CS, REED DJ. Status of glutathione during oxidative stress in the preimplantation mouse embryo. Biol Reprod 1994; 51:1307-1314.

  38. ARECHIGA CF, EALY AD, HANSEN PJ. Evidence that glutathione is involved in thermotolerance of preimplantation mouse embryos. Biol Reprod 1995; 52:1296-1301.

  39. ARECHIGA CF, HANSEN PJ. Response of preimplantation murine embryos to heat shock as modified by developmental stage and glutathione status. In Vitr Cell Dev Anim 1998; 34:655-659.

  40. ARECHIGA CF, STAPLES CR, MCDOWELL LR, HANSEN PJ. Effects of timed insemination and supplemental β-carotene on reproduction and milk yield of dairy cows under heat stress. J Dairy Sci 1998; 81:390-402.

  41. HANSEN PJ, ARECHIGA CF. Strategies for managing reproduction in the heat-stressed dairy cow. J Anim Sci 77/J Dairy Sci 88 1999; Suppl 2:36-50.

  42. BECKETT GJ, ARTHUR JR. Selenium and endocrine systems. J Endocrinol 2005; 184:455-465.

  43. EGER S, DRORI D, KADOORI I, MILLER N, SCHINDLER H. Effects of selenium and vitamin E on incidence of retained placenta. J Dairy Sci 1985; 68:2119-2122.

  44. JASKOWSKI JM. The effect of antepartum doses of selenium-vitamin E combinations on the incidence of puerperal disorders in cattle. Tierarztl Prax 1993; 21:111-116.

  45. ERSKINE RJ, BARLETT PC, HERDT TT, GASTON P. Effects of parenteral administration of vitamin E on health of periparturient dairy cows. J Am Vet Med Assoc 1997; 211:466-469.

  46. LOHRKE B, VIERGUTZ T, KANITZ W, BECKER F, GOLLNITZ K, HURTIENNE A et al. Relationship between oxidant stress and milk productivity in dairy cows. Berl Munch Tierarztl Wochenschr 2005; 118:265-269.




2020     |     www.medigraphic.com