Coria-Lorenzo JJ, Francisco-Revilla EN, Soto-Romero IE, Saavedra-Barrios MA, Gadea-Álvarez T

Language: Spanish
References: 26
Page: 151-159
PDF size: 380.63 Kb.

ABSTRACT

Objective: To describe the incidence (total and by service/year), mortality, site of infection, main etiologic agent of nosocomial infections in neonates (NNI) and relation between site of infection - agent.
Methodology: Retrospective, descriptive, observational, longitudinal study including all neonatal patients, both genders, in the Neonatology, Infectology, Surgery and Intensive Care Units at the National Institute of Pediatrics, Mexico City, from January 1994 to December 1996, with a nosocomial infection (NI) documented by de Nosocomial Infections Committee. We determined the incidence, associated mortality, infection´s site, and etiology in each case, by service and year.
Results: We registered 309 cases of neonatal NI (149 Neonatology, 89 Infectology, 36 ICU and 35 Surgery Units); 40% of the infants were girls, 60% boys; 30% were preterm infants. Global NNI rate: 0.15% . Global NNI mortality was 1.43/100 discharges. Age on admission: 10.3 days (0-45 days); hospitalization duration 36 days (3-161). Main sites of infection: bacteremia in 49% of the cases, neumonia 23%, urinary tract infections 9.2%, surgical wound infections 6.4%. Main pathogens: Klebsiella pneumoniae 38.8%, Coagulase-negative Staphylococci 20.3%, E. coli 13.2%, Enterobacter cloacae 11.6%, Pseudomonas aeruginosa 11%.
Discussion: The rate of mortality and infection locations found by us correlates with those previously reported in several papers; however, the main bacterial etiologies do not, since the most frequent one was K. pneumoniae.

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