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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2003, Number 4

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Rev Biomed 2003; 14 (4)

Serum evidence of Hantavirus infection in people from Yucatan Mexico

Vado-Solís I, Pérez-Osorio C, Lara-Lara J, Ruiz-Piña HA, Cárdenas-Marrufo M, Milazzo ML, Fulhorst CF, Zavala-Velázquez J

Language: Spanish
References: 16
Page: 221-225
PDF size: 30.46 Kb.


ABSTRACT

Introduction. Hantavirus Pulmonary Syndrome (HPS) is an emerging zoonosis in the American Continent characterized by a febrile state and the sudden onset of pulmonary edema; with a fatality rate ›40%. It is caused by members of the virus family Bunyaviridae genus Hantavirus. Rodents are the principal hosts of the hantaviruses that cause HPS. This study was carried out to investigate the presence of hantavirus antibodies in humans and rodent reservoirs in Yucatan State, Mexico.
Material and Methods. Six hundred and sixteen human serum samples from an open population and ninety-two samples from rodents were tested by the ELISA method.
Results. Four human serum samples showed antibodies to hantavirus (0.6% seroprevalence). Antibody titers ranged from 1/320 to › 1/20,000. Age of seropositive people ranged from 2.4 to 80 years old. However none of the rodent samples showed antibodies to hantavirus.
Conclusion. The identification of people with hantavirus antibodies is the first piece of evidence that a hantavirus, antigenically related to agents of HPS, occurs in Yucatán, Mexico.


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