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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2008, Number 2

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Rev Biomed 2008; 19 (2)

Frequency and antimicrobial susceptibility of pathogens isolated from urinary tract infections

Luján-Roca DA, Pajuelo-Camacho GR

Language: Spanish
References: 20
Page: 110-115
PDF size: 167.63 Kb.


ABSTRACT

Introduction. Bacterial infection of the urinary tract is a common problem in the medical practice, the susceptibility and etiology of the microorganisms that produce it can vary through time.
Objective. To investigate the frequency and antimicrobial susceptibility of uropathogens.
Material and Methods. A cross-sectional and a descriptive analysis were carried out in a local clinic in Lima-Peru between January and March of 2002. Frequency and susceptibility to antibiotics of pathogenic microorganisms recovered from urinary infections were studied. The method of Kirby-Bauer with the recommendations of the NCCLS was used on urine cultures for antimicrobial susceptibility testing.
Results: Out of a total of 479 urine cultures, 105 (p › 0.05) were culture positive. The recovered microorganisms were Escherichia coli (69.5%), non hemolytic Streptococci (9.5%), Proteus mirabilis (6.7%), Staphylococcus aureus (4.8%) and coagulase negative Staphylococci (4.8%). On the antimicrobial susceptibility testing, the antibiotic ampicilline-sulbactam and amikacin showed high activity (80-100%) against enteric Gram negative bacilli and Gram positive cocci. Nalidixic acid and nitrofurantoine showed moderate activity (32.8-55.4%) for E. coli and ceftriaxona showed good activity (90%) against these bacteria.
Conclusions. It was found that E. coli was the most frequent microorganism in ITU and that the best antimicrobial activity was shown by ampicilline-sulbactam and amikacin against all the recovered bacteria.


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