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ISSN 0187-5337 (Print)
Instituto Nacional de Perinatología

2001, Number 4

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Perinatol Reprod Hum 2001; 15 (4)

Efecto de los antiepilépticos sobre la salud ósea de las mujeres en edad reproductiva

Gutiérrez-Valenzuela V, Casanueva E

Language: Spanish
References: 21
Page: 262-268
PDF size: 111.17 Kb.


ABSTRACT

Epilepsy is a common neurologic condition that is successfully controlled by specific drugs. These drugs may alter calcium metabolism but it is still not well known how, could be related to an decreased mineral bone density.
Pregnant women require special attention in relation to calcium in the third trimester due to an increased calcium requirement by the fetus and by the need of preparing themselves for a successful lactation process.
In relation to all the information found in the literature associating anticonvulsivant consumption and calcium turnover it would be of great importance to study if pregnant or lactating epileptic women really have an exacerbated calcium loss and if this is followed by an irreversible decreased mineral bone density compared with healthy pregnant or lactating women or if the newborn of and epileptic mother have mineral bone density alterations due to anticonvulsivant drug effect.
If all the above is true, women with epilepsy will require a specific calcium recommendation to protect them of developing osteopenia or osteoporosis during their climacteric days.


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