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Boletín Médico del Hospital Infantil de México

2009, Number 2

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Bol Med Hosp Infant Mex 2009; 66 (2)

Associated factors to complications in acute pancreatitis in children

García-Dávila M, Villalpando-Carrión S, Heller-Rouassant S, Solís-Perales NE, Ortiz-Ramírez OE, López-Contreras N

Language: Spanish
References: 14
Page: 160-166
PDF size: 138.24 Kb.


ABSTRACT

Introduction. Acute pancreatitis is an uncommon disease in childhood that lacks an adequate scale for predicting disease severity. The objective of this study was to determine the main factors that predict severe acute pancreatitis.
Methods. A chart review of children under 17 years of age hospitalized with diagnosis of acute pancreatitis from January 2001 to December 2006 was conducted. Demographics, local and systemic complications, nutritional status and nutritional support were analyzed.
Results. Forty-seven patients were included with a mean age of 8.7 ± 4 years. Weight for height (W/H) was 106 ± 21% and BMI 17.3 kg/m2 (zBMI 0.031 ± 0.21); 13% of patients were overweight, with W/H greater than 110%. Thirty-eight percent of patients developed complications; these patients, compared with patients without complications, showed a difference in W/H, BMI and zBMI (P ‹0.01), but not in other parameters. Nutritional support started on average at 5.7 days with parenteral nutrition in 89% of cases, and enteral feeding after 13 ± 10 days of fasting.
Conclusion. In our study, more than 50% of patients had oncological diseases, and 57% presented pharmacological etiology. Prognosis factors were analyzed and no statistical differences in serum leucocytes, amylase and lipase were found between patients with or without complications; most complications were found in patients with higher W/H and BMI. This association suggests that future prognosis scales of acute pancreatitis in children should include these variables.


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