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2001, Number 2

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Rev Mex Anest 2001; 24 (2)

Evaluación de una dosis de Morfina vs. Morfina y clonidina por vía epidural en cirugía de abdomen bajo

Campos GS, Álvarez VJC

Language: Spanish
References: 20
Page:
PDF size: 61.37 Kb.


ABSTRACT

Objetive: To evaluate the analgesic effect, as well as the colateral effects of the administration of single dose of 2 mg of morphine against a single dose of 1 mg morphine + 150 mcg clonidine. Material and methods: 60 patients of the feminine sex were studied, ASA I and II, which were divided in 2 groups: (30 patients) administered 1 mg morphine + 150 mcg clonidine and group B (30 patients) administered 2mg morphine; in both groups the drug was administered during the transoperative using a catheter epidural placed previously in T11-T12.The following variables were determined: pain, nausea, vomit, pruritus, heart frequency, arterial pressure, SpO2, and sedation degree when arriving to recovery room (time 0), at the 30’, 60’, 2, 4, 8, 12 and 24 hours. Results: The following variables were smaller in the group A: pain at 0’, 30’, 2, 4, 8, 12 and 24 hours, as well as nausea at the 0’, 30’, 60’, 2, 4 and 8 hours; the vomit at 0’ and 30’; the pruritus at the 8 hours; the heart frequency at 30’ and 60’; the arterial pressure at 30’, 60’, 2, 4 and 8 hours. Finally the degree of the patients’ sedation in the group A it was 2 and the patients of the group B it was 1. Discusion: In surgery of low abdomen (hysterectomy) the administration of a single dose of 1 mg morphine + 150 mcg clonidine has the same analgesic effect in the postoperative than 2 mg morphine, but with smaller colateral effects.


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