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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2008, Number 6

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Rev Mex Oftalmol 2008; 82 (6)

Comparación de la presión intraocular en ojos con edema macular tratados con acetónido de triamcinolona intravítrea con y sin conservadores

Altamirano-Vallejo JC, Mora-Ríos LE, Castellanos-González MA, Ruiz-Orizaga G, Cisneros-Gómez SM

Language: Spanish
References: 31
Page: 394-402
PDF size: 60.29 Kb.


ABSTRACT

Objective: To compare the incidence of ocular hypertension after the intravitreal injection of triamcinolone acetonide with and without preservative.
Material and methods: Retrospective analysis of the clinical charts of patients with macular edema secondary to different pathologies. We established two groups. Group 1 included injected eyes with triamcinolone acetonide with preservative and group 2 included injected eyes with the preservative-free product. We compared the intraocular pressure at baseline and week 1, month 1 and month 3 after the intravitreal injection.
Results: Ninety one eyes of eighty eight patients were included, 61 in group 1 and 30 in group 2. Elevation of the intraocular pressure after injection was higher for group 1, reaching statistic significance at all the corresponding measurements. In group 1, 36% of the eyes required medical or surgical treatment in order to control the intraocular pressure, while medical treatment was required only in 3% of the eyes included in group 2.
Conclusions: Intravitreal injection of preservative-free triamcinolone acetonide induced lower incidence of ocular hypertension when compared to the formulation with preservative.


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