2008, Number 1
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Med Int Mex 2008; 24 (1)
Lipodystrophy syndrome in HIV-infected patients with antirretroviral therapy
Castro SC, Santos RA, Salazar RJC, Díaz RI, Góngora BR, González MP
Language: Spanish
References: 29
Page: 8-15
PDF size: 171.37 Kb.
ABSTRACT
Background: Lipodystrophy syndrome in HIV-infected patients receiving antiretroviral therapy is characterized by loss of peripheral subcutaneous adipose tissue and increase of central adipose tissue.
Objective: To determine the prevalence of lipodystrophy syndrome in a group of HIV-infected patients who receive antiretroviral therapy, at Yucatan, Mexico.
Material and method: Prospective, observational, descriptive and cross-sectional study over 123 patients with at least one year of antiretroviral therapy at Hospital General Agustín O’Horan. To collect its clinical and demographic data, it was applied a questionnaire to each patient. Anthropometric measurement in their skin folds (cheek, biceps, triceps, and femur) was made, and BMI and the waist/hip index were calculated.
Results: Prevalence of lipodystrophy syndrome was 16%, 5% with hypertrophy, 40% with atrophy and 55% with a mixed pattern. Presence of lipodystrophy syndrome was associated to the duration of the antiretroviral therapy.
Conclusion: Prevalence of lipodystrophy syndrome, present in Yucatan’s patients, was lower to that reported in other countries. Anthropometry offers a low-cost alternative to diagnose this disease.
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