Sordo PJA, Robles MSG

Language: Spanish
References: 30
Page: 81-86
PDF size: 190.94 Kb.

ABSTRACT

Background
The harmful effect of certain foods in gastroesophageal reflux disease (GERD) is well established, however, the benefit of the medical-dietary handling has not been sufficiently studied.
Objective
To compare symptoms and nasopharyngolaryngoscopic changes before and after the medical-dietary handling in patients diagnosed with GERD.
PATIENTs and methods
This was a prospective, longitudinal and analytical (before, after) study carried out from May 2007 to February 2008. Fifty GERD patients gave their informed consent and were recruited. The treating physician gathered information about the symptoms’ severity (pyrosis, dysphagia, thoracic pain, epigastric pain, voice changes, pharyngeal clearing, posterior discharge, postprandial cough and dyspnea) and their association to certain foods, before and after both medical (antiacids, prokinetics) and dietary (reduction of foods that exacerbate the condition) treatments. A nasopharyngolaryngoscopy was conducted, and smoking and body mass index (BMI) were evaluated before and after treatment. The statistical analysis included data description (mean, SD) and comparisons (paired T-Student test).
Results
The age of participants ranged from 18 to 74 years (mean ± SD = 40.7 ‹ 11.9). Fifty four percent of the patients were males and 30% were smokers. High fat foods, chocolate, coffee, alcohol, tomato, orange and soda were associated to GERD exacerbation. After medical and dietary treatment, there was a decrease in: BMI (p ‹ 0.001), intake of harmful foods (p ‹ 0.001), symptoms (p ‹ 0.001), and nasopharyngolaryngoscopic findings (p ‹ 0.001).
Conclusions
The dietary and medical management reduced the symptoms associated to GERD. It would be important to perform a blind and controlled random clinical trial to demonstrate the individual weight of medical and dietary interventions in GERD’s management.

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