Martínez RG, García OLE, Constantino CF, Solís CK, Méndez ARE

Language: English/Spanish
References: 19
Page: 335-340
PDF size: 192.30 Kb.

ABSTRACT

The aim of this work is to describe the clinical and pathological fi ndings in a dog with gallbladder mucocele, in order to contribute to study this rare disease. The clinical case corresponds to a twelve-year-old, male, German Shepherd dog that presented jaundice and acute abdominal pain. Blood biochemistry revealed increased liver enzymes, hyperbilirrubinemia and hypercholesterolemia. The ultrasonography study showed gallbladder wall thickening and ecogenic uniform sediment, interpreted as biliary sludge. The dog was euthanized due to his poor condition. At necropsy it was found gallbladder mucocele and the histopathological diagnosis was biliary cystic mucinous hyperplasia. This pathology should be considered as a differential clinical diagnosis of any hepatobiliary disease accompanied by cholestasis. Ultrasonography is the main tool for the diagnosis of gallbladder mucocele and the recommended treatment is cholecystectomy.

REFERENCES

1. 1.Besso JG, Wrigley RH, Gliatto JM, Webster CRL. Ultrasonographic appearance and clinical fi ndings in 14 dogs with gallbladder mucocele. Vet Radiol Ultrasound 2000, 41:261-271.

2. 2.Pike FS, Berg J, King NW, Penninck DG, Webster CR.Gallbladder mucocele in dogs: 30 cases (2000-2002). J Am Vet Med Assoc 2004, 224:1615-1622.

3. 3.Albores JS, Stella MD, Defortuna MD, Smothermon WE. Primary papillary hyperplasia of the gallbladder and cystic and common bile ducts. Hum Pathol 1990, 21:228-231.

4. 4.Newell SM, Selcer BA, Mahaffey MB, Gray ML, Jameson PH, Cornelius LM et al. Gallbladder Mucocele causing biliary obstruction in two dogs: ultrasonographic, scintigraphic, and pathological fi ndings. J Am Anim Hosp Assoc 1995, 31:467-472.

5. 5.Reindel JF, Evans MG. Cystic mucinous hyperplasia in the gallbladder of a ferret. J Comp Pathol 1987, 97:601-604.

6. 6.Fell BF, Robinson JJ, Watson M. Cystic hyperplasia of the gallbladder in breeding ewes. J Comp Path 1983,93:171-178.

7. 7.Jones TC, Hunt RD, King NW. Veterinary pathology. 6a ed. Baltimore:Lippincott Williams & Wilkins, 1997.

8. 8.Worley RD, Hottinger AH, Lawrence JH. Surgicalmanagement of gallbladder mucocele in dogs: 22 cases (1999-2003). J Am Vet Med Assoc 2004, 225:1418-1422.

9. 9.Rivers JB, Walter PA, Johnston GR, Merkel LK, Hardy RM. Acalculous cholecystitis in four canine cases: ultrasonographic fi ndings and use of ultrasonographicguide,percutaneous cholecystocentesis in diagnosis. JAm Anim Hosp Assoc 1997, 33:207-214.

10. 10.Kelly RW. The liver and biliary system, In: Jubb FV, Kennedy CP, Palmer N, editors. Pathology of domestic animals. 4a ed, Vol II, California:Academic Press, 1993:402-403.

11. 11.Owens SD, Gossett R, McElhaney RM, Christopher MM,Shelly MS. Three cases of canine bile peritonitis with mucinous material in abdominal fl uid as the prominent cytologic fi nding. Vet Clin Pathol 2003, 32:114-120.

12. 12.Mawdesley-Thomas LE, Noel PR. Cystic hyperplasia of the gallbladder in the beagle associated with the administration of progestational compounds. Vet Rec 1967, 80:658-659.

13. 13.Nelson LW, Kelly WA. Progestogen–related gross and microscopic changes in female beagles. Vet Pathol 1976, 13:143-156.

14. 14.Goyings LS, Sokolowski JH. Histologic evaluation of gallbladder in progestogen-treated bitches. Am J Vet Res 1975, 36:1263-1264.

15. 15.Strombeck DR, Guilford GW. Enfermedades digestivas de los animales pequeños. 2ª ed. Buenos Aires: Inter.-Médica, 1995.

16. 16.Neer TM. A review of disorders of the gallbladder and extrahepatic biliary tract in the dog and cat. J Vet Intern Med 1992, 6:186-192.

17. 17.Leveille CR. Diagnóstico de laboratorio de la enfermedad hepatica. En: Ettinger SJ, Feldman EC, editores. Tratado de medicina interna veterinaria. Bogotá,Colombia: Inter-Médica, 2002:1420-1437.

18. 18.Reed AL. Ultrasonographic fi ndings of diseases of the gallbladder and biliary tract. Vet Med 1995:950-958.

19. 19.Brömel C, Barthez PY, Léveillé R, Scrivani PV. Prevalence of gallbladder sludge in dogs as assessed by ultrasonography. Vet Radiol Ultrasound 1998, 39:206-210.