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2008, Number 4

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Rev Mex Anest 2008; 31 (4)

Preventive effect 100 mg of tramadol for post-surgical pain

Paz-Estrada C, Belette-Alpajón E

Language: Spanish
References: 25
Page: 278-281
PDF size: 59.37 Kb.


ABSTRACT

Objective: To evaluate the analgesic effectiveness of tramadol in the prevention of postoperative pain in patients who underwent acute appendicitis. Material and methods: It harpvenedent tion of theryned i by ultrasound was carried out a controlled, double-blind, and randomized clinical study, on, patients who have been operated due to acute appendicitis at the hospital «Guillermo Luis Fernández Hernández-Baquero», Moa, Holguín, Cuba, during the months going from October 2005 to May 2006; 86 patients were selected. They were divided into two groups of 43 patients each. Group I: tramadol 100 mg and; Group II: intravenous metamizol 2 g, both 30-minutes treatments were given before the surgery. General anesthesia was applied; and systolic blood pressure, cardiac rate and hemoglobin saturation (HbSat) were recorded during several stages of the anesthetic process: basal, transoperative, and at the first 180 minutes of the postoperative, as well as the most frequent adverse effects. Pain intensity was measured in the postoperative period through the Analogous Visual Scale (AVS). Results: Pain significantly decreased through the use of tramadol when compared with the placebo (p ‹ 0.05); nausea was prevailing (16.3%), followed by vomits in the 13% of the patients who used tramadol. Conclusions: Tramadol at a dosage of 100 mg in the preoperative period contributes to the reduction of the intensity of postoperative pain.


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