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Medicina Universitaria

2007, Number 34

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Med Univer 2007; 9 (34)

Prevalence and risk factors for necrotizing enterocolitis in neonates between 1000 and 1500 g in the neonatal intensivecare unit in the Dr. José Eleuterio González University Hospital from august 1, 2005 to july 31, 2006

Miranda BI, Ochoa CEC, Rodríguez BI, Ábrego MV

Language: Spanish
References: 22
Page: 13-19
PDF size: 131.43 Kb.


ABSTRACT

Background: Necrotizing enterocolitis is the most common gastrointestinal disease in the newborn.
Objective: To know the prevalence and the associated risk factors of necrotizing enterocolitis in newborns from 1,000 to 1,500 g at the Neonatal Intensive Care Unit of the Dr. José Eleuterio González University Hospital.
Material and method: This is an observational, retrospective, and analytic case controlled study. Data was collected from the medical charts of infants with a birth weight of 1,000 to 1,500 g, admitted to the Neonatal Intensive Care Unit that were born from August 1, 2005 to July 31, 2006 at the University Hospital. Infants were excluded if they were born in another hospital, or if they had congenital malformations. The data was analyzed using a Chi Square, Student’s t test and odds ratio.
Results: Fifty-five patients had inclusion criteria, and 18% developed necrotizing enterocolitis II or more. The associated risk factors for the development of necrotizing enterocolitis were Apgar score less than 5 at the first minute, nasal cannula with continuous positive airway pressure, aminophylline administration and late onset sepsis (p ‹ 0.05).
Conclusion: In our study, the prevalence of necrotizing enterocolitis is 18%, higher than that reported in developed countries, and that observed in private hospitals in developing countries, although the mortality is lower. The main risk factors were associated with ischemiareperfusion and infection.


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