medigraphic.com
Colegio de Medicina Interna de México.

2007, Number 3

<< Back Next >>

Med Int Mex 2007; 23 (3)

Adenocarcinoma of prostate metastases to distal third of leg. Rare case report

Rivera ZDJ, Estrada HMR, Peña MS, Parraguirre MS, Reyes CMM, Estrada HLO, Romero SL, Ríos BER

Language: Spanish
References: 13
Page: 248-250
PDF size: 349.39 Kb.


ABSTRACT

It is presented the case of a 62 year-old man with diagnosis of prostate carcinoma located in pelvis with metastasis to distal third of leg and calcaneus bone as a rare variant of bony dissemination. The adenocarcinoma of prostate tends to affect bone in a high percentage; however the customary location is axial form. It is made biopsy with histopathology report of adenocarcinoma of prostate with sum of Gleason = 6; prostate specific antigen of 60 ng/dL, without bony metastases. Six months later it is appreciated metastases in the distal third of straight leg with affection of calcaneus's bone, which is corroborated by biopsy.


REFERENCES

  1. Weber KL, Gebhardt MC; Council of Musculoskeletal Specialty Societies of the American Academy of Orthopaedic Surgeons. What’s new in musculoskeletal oncology. J Bone Joint Surg Am 2003;85-A(4):761-7.

  2. Roodman GD. Mechanism of bone metastases. N Engl J Med 2004;350(16):1655-64.

  3. Cotran RS, Kumar V, Collins ST. Patología estructural y funcional de Robbins. 6ª ed. Madrid: McGraw-Hill Interamericana, 1999.

  4. MacLennan GT, Resnick MI, Bostwick DG. Prostate, seminal vesicle and prostatic uretra. In: MacLennan GT, Resnick MI, Bostwick DG, editors. Pathology for urologists. 1st ed. London: Saunders, 2003.

  5. Cooper CR, Chay CH, Gendernalik JD, Lee HL, et al. Stromal factors involved in prostate carcinoma metastases to bone. Cancer 2003;97(3 Suppl):739-47.

  6. Smith PH, Bono A, DaSilva C Et al. Some limitations of the radioisotope bone scan in patients with metastatic prostate cancer. Cancer 1990;60:1009.

  7. Golztman D. Mechanisms of the development of osteoblastic metastases. Cancer 1997;80(8 Suppl):1581-7.

  8. Oefelein MG, Grayhack JT, McVary KT. Survival after radical retropubic prostatectomy of men with clinically localized high grade carcinoma of the prostate. Cancer 1995;76(12):2535-42.

  9. Epstein JI, Carmichael M, Walsh PC. Adenocarcinoma of the prostate invading the seminal vesicle: definition and relation of tumor volume, grade and margins of resection to prognosis. J Urol 1993;149(5):1040-5.

  10. Kozlowski JM, Grayhack JT. Carcinoma of the prostate. In: Gillenwater JY, Grayhack JT, Howards SS, Mitchell ME. Adult and pediatric urology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.

  11. Libson E, Bloom RA, Husband JE, Stoker DJ. Metastatic tumors of bones of the hand and foot. A comparative review and report of the 43 additional cases. Skeletal Radiol 1987;16(5):387-92.

  12. Sciuk J, Kirchner B. Atypical bone metastases in prostate cancer. Aktuelle Radiol 1991;1(3):134-7.

  13. Oh WK, Loda M, Kantoff PW, Janicek M. Progressive sclerosis of isolated foot metastasis of prostate cancer. J Urol 2002;167(3):1392.




2020     |     www.medigraphic.com