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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2003, Number 5

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Rev Mex Oftalmol 2003; 77 (5)

Coriorretinitis neonatal por citomegalovirus sin manifestaciones sistémicas. Reporte de un caso

Prado-Serrano A, Hernández-Salazar L, García-Regil P

Language: Spanish
References: 30
Page: 188-192
PDF size: 157.23 Kb.


ABSTRACT

Cytomegalovirus (CMV) is the most common congenital infection, occurring in up to 2.2% of all live births. The virus is known to infect many organs, including the liver, lung, brain, bone marrow and eye. Active CMV infection can cause notable morbidity and mortality in immunocompromised patients and destructive chorioretinitis, which is recognized by its distinctive appearance on ophthalmologic examination as white yellow areas of retinal necrosis with hemorrhages.
The finding of chorioretinitis has been associated with severe systemic infection, usually resulting in central nervous system impairment, permanent mental and motor retardation and sometimes death. We report an unusual case of chorioretinitis caused by cytomegalovirus in an infant without other evidence of severe cytomegalic inclusion disease. The diagnosis was established by culturing virus from throat and urine of both mother and child, showing a completely normal development in a three-year follow - up period


REFERENCES

  1. Alford C, Stango S, Pass R y cols.: Epidemiology of cytomegalovirus. En: Nahmias A, Dowdle W, Schinazi R (eds). The human herperviruses. New York, Elsevier Science Inc; 1981:159-171.

  2. Stagno S, Pass R, Dworsky M y cols.: Congenital and perinatal cytomegalovirus infections. Semin Perinatol 1983; 7:31-42.

  3. Alford C, Stagno S, Pass R, Britt W: Congenital and perinatal cytomegalovirus infections. Rev Infect Dis 1990; 12 (suppl 7): S 745-S753.

  4. Baumal C, Levin A, Kavalec C, Petric M, Khan H, Read S: Screening for cytomegalovirus retinitis in children. Arch Pediatr Adolesc Med 1996; 150:1186-1192.

  5. Hirsch M: Infección por citomegalovirus. En : Isselbacher K (ed). Harrison. Principios de Medicina Interna. Vol I. 13a ed., España, Interamericana-McGraw Hill, 1994. p. 922-925.

  6. Baumal C, Duker J: Cytomegalovirus retinitis. En: Duane’s Ophthalmology. CD 2003 ed.

  7. Prado A: Tratamiento de la retinitis por citomegalovirus en sujetos con síndrome de inmunodeficiencia adquirida. Rev Mex Oftalmol 2000; 74:109-116.

  8. Baumal C, Levin A, Read S: Cytomegalovirus retinitis in immunosuppressed children. Am J Ophthalmol 1999; 127:550-558.

  9. Cinatl J, Bittoova M, Margraf S, Vogel J, Cinatl J, Preiser W, Doerr H: Cytomegalovirus infection decreases expression of thrombospondin -1 and –2 in cultered human retinal glial cells: effects of antiviral agents. J Infect Dis 2000; 182:643-651.

  10. Prado A, Tenorio G: Infecciones oculares en el sindrome de inmuniodeficiencia adquirida. En: Higuera F (ed). Infectología, México, Prado, 1996; 309-327.

  11. Holland G, Buhles J, Mastre V y cols.: A controlled retrospective study of ganciclovir treatment for cytomegalovirus retinopathy: use of a standarized system for the assesment of disease outcome. Arch Ophthalmol 1989; 107:1759-1766.

  12. Hennis H, Scott A, Apple D: Cytomegalovirus retinitis. Surv Ophthalmol 1989; 34: 193-203.

  13. Becroft D: Prenatal cytomegalovirus infection: epidemiology, pathology and pathogenesis. Perspect Pediatr Pathol 1981; 6:203-241.

  14. Pass R: Cytomegalovirus infection. Pediatrics Review. 2002; 23(5):163-169.

  15. Frenkel L, Gaur S, Tsolia M y cols.: Cytomegalovirus infection in children with AIDS. Rev Infect Dis 1990; 12 ( suppl 7):820-825.

  16. Diagnosis of cytomegalovirus infection Rev Infect Dis 1988 (suppl 3): S 468-476.

  17. Berenberg W, Nankervis G: Long term follow-up of cytomegalic inclusion disease of infancy. Pediatrics 1990; 46:403-410.

  18. Grundy J: Virologic and pathogenic aspects of cytomegalovirus infection. Rev Infect disease 1990; 12 (suppl 7):711-719.

  19. Weller T: The clinical spectrum of cytomegalovirus infection. En: Nahmias A, Dowdle W, Schinazi R y cols. The human herpesviruses. New York, Elsevier Science Inc; 1981: 20-30.

  20. Boppana S, Amos C, Brit W y cols.: Late onset and reactivation of chorioretinitis in children with congenital cytomegalovirus infection. Pediatr Infect Dis J 1994; 13: 1139-1144.

  21. Peters M, Moeller H, Russell-Eggitt I: Cytomegalovirus retinitis in AIDS. Arch Dis Child 1995; 72:54-55.

  22. Grundy J: Virologic and pathogenic aspects of cytomegalovirus infection. Rev Infect Dis 1990; 12 (suppl 7):711-719.

  23. Istas A, Demmler G, Dobbins J y cols.: National congenital cytomegalovirus disease registry collaborating group. Surveillance for cytomegalovirus disease: a report from the National Congenital Cytomegalovirus Disease Registry. Clin Infect Dis 1995; 20: 665-670.

  24. Walton R, Whitcup S, Mueller B y cols.: Combined intravenous ganciclovir and foscarnet for children with recurrent cytomegalovirus retinitis. Ophthalmology 1995; 102:1865-1870.

  25. Rook A: Interactions of cytomegalovirus with the human immune system. Rev Infect Dis 1988; 10 (Suppl 3):460-467.

  26. Holland G, Sidikaro Y, Kreiger K: Treatment of cytome-galovirus retinopathy with ganciclovir. Ophthamology 1987; 94:815-823.

  27. Stagno S, Reynolds D, Amos C y cols.: Auditory and visual defects resulting from symptomatic and sub clinical congenital cytomegaloviral and toxoplasma infections. Pediatrics 1977; 59:669-678.

  28. Jones C, Issacs D: Predicting the outcome of symptomatic congenital cytomegalovirus infection. J Paediatr Child Health 1995; 31:70-71.

  29. Kanski J: Oftalmología Clínica. 4a ed. España, Harcourt, 2000. p. 252-254.

  30. Holland G, Shuler J: Progression rates of cytomegalovirus retinopathy in ganciclovir treated and untreated patients. Arch Ophthalmol 1992; 110:1435-1442.




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