Babayán JI, Rodríguez MHA, Peña GS, Pérez OO

Language: Spanish
References: 13
Page: 318-320
PDF size: 102.74 Kb.

ABSTRACT

Ocular and conjunctival hemangiosarcoma show a low incidence. No case reports were found in the national literature to the best of our knowledge. The most frequent sites are the breast, after radiations, liver, gastrointestinal tract, heart and large vessels, as well as skin including face and scalp.
The case of a 76 year-old male with a scalp hemangiosarcoma, diagnosed three months before and treated with surgery and chemotherapy, is presented. He was seen at the ophthalmologic clinic with a six millimetres, well defined, painless, reddish nodule in the conjunctiva of the left lower lid, which was removed because of the previous diagnosis of neoplasia. The gross pathological study revealed a well defined, hemorrhagic spongy mass. Microscopically, small vessels of different diameter were seen, which were occupied with neoplastic epithelioid and spindle cells, consistent with hemangiosarcoma. After confirming that the primary was in the liver, the patient died eight months later, although without showing recurrence of the lid lesion.

REFERENCES

1. Hodgson NC, Bowen-Wells C, Moffat F, Franceschi D, Avisar E. Angiosarcomas of the breast: a review of 70 cases. Am J Clin Oncol 2007; 30(6):570-3.

2. Bhardwaj M, Gautam RK, Sharma PK, Kar HK, Magoon N, Sharma A. Angiosarcoma of scalp: a case report. Indian J Pathol Microbiol 2005; 48(4):497-9.

3. Mehrens C, Anvari L, Grenzebach UH, Metze D. Unilateral eyelid swelling as an initial manifestation of angiosarcoma. Hautarzt 2000; 51(6):419-22.

4. Gündüz K, Shields JA, Shields CL, Eagle RC Jr, Nathan F. Cutaneous angiosarcoma with eyelid involvement. Am J Ophthalmol 1998; 125(6):870-1.

5. Bray LC, Sullivan TJ, Whitehead K. Angiosarcoma of the eyelid. Aust N Z J Ophthalmol 1995; 23(1):69-72.

6. Hufnagel T, Ma L, Kuo TT. Orbital angiosarcoma with subconjunctival presentation. Report of a case and literature review. Ophthalmology 1987; 94(1):72-7.

7. Kikuchi H, Kurokawa M, Setoyama M: Two cases of angiosarcoma of the face. J Dermatol 2004; 31(1):47-50.

8. Fayette J, Martin E, Piperno-Neumann S, Le Cesne A, Robert C y cols. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases. Ann Oncol 2007; 18(12):2030-6.

9. Schuller DE, McCaughan JS Jr, Rock RP. Photodynamic therapy in head and neck cancer. Arch Otolaryngol 1985; 111(6):351-5.

10. Tada Y, Takiguchi Y, Terada J, Yoshida T, Shinozaki A, Sakao S y cols. A case of angiosarcoma of pelvis with pulmonary metastases which responded to paclitaxel. Gan To Kagaku Ryoho 2007; 34(13):2275-7.

11. Nagano T, Yamada Y, Ikeda T, Kanki H, Kamo T, Nishigori C. Docetaxel: a therapeutic option in the treatment of cutaneous angiosarcoma: Report of 9 patients. Cancer 2007; 110(3):648-51.

12. Masuzawa M, Mochida N, Amano T, Fujimura T, Hamada Y y cols. Evaluation of recombinant interleukin-2 immunotherapy for human hemangiosarcoma in a SCID mice model (WBSCID). J Dermatol Sci 2001; 27(2):88-94.

13. Kojima K, Okamoto I, Ushijima S, Yoshinaga T, Kitaoka M y cols. Successful treatment of primary pulmonary angiosarcoma. Chest 2004; 126(1):317-8; 318.