2008, Number 5
<< Back Next >>
Rev Mex Oftalmol 2008; 82 (5)
Análisis de la capa de fibras nerviosas posterior a fotocoagulación en retinopatía diabética
Saucedo A, Levine A, Celis B, Ramirez A
Language: Spanish
References: 26
Page: 284-291
PDF size: 244.53 Kb.
ABSTRACT
Purpose: To determine by Optic Coherence Tomography (OCT) if there are changes in the nerve fiber layers in diabetic retinopathy after photocoagulation.
Patients and methods: This is a prospective, longitudinal, comparative and observational study. Patients with diabetic retinopathy were included. We divided patients into two groups: Group 1 included patients without treatment and Group 2 included patients who have been photocoagulated. Both groups underwent photocoagulation and nerve fiber layer thickness analysis was done before and 4 to 6 weeks after treatment.
Results: We included 33 eyes. Mean age was 56 years old. In fifty percent of cases in Group 1 and 56.25% in Group 2 peripapilar nerve fiber layer thickness were decreased in the temporal and inferior area. More changes were seen in Group 1: a diminution in the superior, nasal, inferior and temporal area (mean 39.5 microns) compared with 26.25 in Group 2 (p›0.05). Minimal changes were observed in mean macular nerve fiber layer thickness.
Conclusions: Nerve fiber layer thickness may change after photocoagulation, producing damage in the internal layer of the retina and not only in the outer ones.
REFERENCES
Bonafonte Royo S, García CA. Retinopatía diabética. Ed. Harcourt. España, 1996.
Apple D y cols. Experimental argon laser photocoagulation. I Effects on retinal nerve fiber layer. Arch Ophthalmol 1976; 94:137-144.
Wallow I, Sponsel W, Stevens T. Clinicopathologic correlation of diode laser burns in monkeys. Arch Ophthalmol 1991; 109:648-653.
Brancato R, Pratesi R, Leoni G, Trabucchi G, Vanni U. Histopathology of diode and argon laser lesions in rabbit retina. Invest Ophthalmol Vis Sci 1989; 30(7):1054-1510.
Thomas E, Apple D, Swartz M, Norman D. Histopathology and Ultrastructure of krypton and argon laser lesions in a human retina-choroid. Retina 1984; 4(1):22-39.
Apple D, Goldberg M, Wyhnny G. Histopathology and ultrastructure of the argon laser lesion in human retinal and choroidal vasculatures. Am J Ophthalmol 1973; 75(4):595-609.
Hammilton MB. Histopathology of ruby and argon lesions in monkey and human retina. A comparative study. Br J Ophthalmol 1975; 59:610-629.
L’Esperance FA Jr. Ophthalmic lasers: photocoagulation, photoradiation and surgery, 2nd ed. St Louis: CV Mosby, 1983; 279-84.
Anderson DR. Ascending and descending optic atrophy produced experimentally in squirrel monkeys. Am J Ophthalmol. 1973; 76:693-711.
Johns K, Martin T, Feman S. The effect of panretinal photocoagulation on optic nerve cupping. Ophthalmol 1989; 96(2):211-216.
Toth C y cols. Argon laser retinal lesions evaluated in vivo by optical coherence tomography. Am J Ophthalmol 1997; 123:188-198.
Jaffe G, Caprioli J. Perspective. Optical coherence tomography to detect and manage retinal disease and glaucoma. Am J Ophthalmol 2004; 137:156-169.
Beltagi T y cols. Retinal nerve fiber layer thickness measured with optical coherence tomography is related to visual function in glaucomatous eyes. Ophthalmol 2003; 110:2185-2191.
Hess D y cols. Macular and retinal nerve fiber layer analysis of normal and glaucomatous eyes in children using optical coherence tomography. Am J Ophthalmol 2005; 139:509-517.
Varma R, Bazzaz S, Lai M. Optical tomography-measured retinal nerve fiber layer thickness in normal latinos. Invest Ophthalmol Vis Sci 2003; 44:3369-3373.
Bowd C, Weinreb R, Williams J, Zangwill L. The retinal nerve fiber layer tickness in ocular hypertensive, normal, and glaucomatous eyes with optical coherence tomography. Arch Ophthalmol 2000; 118:22-26.
Bhumenthal E y cols. Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography. Ophthalmol 2000; 107:2278-2282.
Schuman J y cols. Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmol 1996; 103:1889-1898.
Pieroth L y cols. Evaluation of focal defects of the nerve fiber layer using optical coherence tomography. Ophthalmol 1999; 106:570-579.
Jones A, Sheen N, North R, Morgan J. The Humphrey optical coherence tomography scanner: quantitative analysis and reproductibility study of the normal human retinal nerve fibre layer. Br J Ophthalmol 2001; 85:673-677.
Chauhan D, Marshall J. the interpretation of optical coherence tomography images of the retina. Invest Ophthalmol Vis Sci. 1999; 40:2332-2342
Varma R, Skaf M, Barron E. Retinal nerve fiber layer thickness in normal human eyes. Ophthalmol 1996; 103:2114-2119.
Repka M, Quigley H. The effect of age on normal human optic nerve fiber number and diameter. Ophthalmol 1989; 96:26-32.
Lee V, Mok K, Phil M. Retinal nerve fiber layer measurement by nerve fiber analyzer in normal subjects and patients with glaucoma. Ophthalmol 1999; 106:1006-1008.
Schlottmann P y cols.. Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry. Invest Ophthalmol Visc Sci 2004; 45:1823-1829.
Ulbig M, Arden G, Hamilton P. Color contrast sensitivity and pattern electroretinographic findings alter diode and argon laser photocoagulation in diabetic retinopathy. Am J Ophthalmol 1994; 117:583-588.