2007, Number 2
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Rev Mex Oftalmol 2007; 81 (2)
Correlación morfológica y funcional en edema macular diabético
Fernández MEL, Fernández CL, Quiroz MH
Language: Spanish
References: 27
Page: 65-70
PDF size: 81.09 Kb.
ABSTRACT
Purpose: To determine if correlation between macular thickness evaluated by optical coherence tomography (OCT) and electrical response measured by multifocal electroretinogram (mERG) exists and the relationship of each one of these modalities with the visual acuity in patients with clinical significant macular edema (f-DCSME).
Methods: Macular thickness was determined with OCT. Macular function was determined through mERG. Pearson correlation between electric function of macula and best-corrected visual acuity (BCVA), between macular thickness measurements and BCVA, and between OCT and ERGm measurements were determined.
Results: Twenty-six eyes of thirteen patients were studied. Average age was 60.5 years. BCVA of study group was –0.34 (log MAR). Patients with clinical diagnosis of f-DCSME showed at least one thickened area on the macular topography map. Average macular thickness of study group was 264.2 mm; central foveal thickness was 235.7 mm. In the mERG the wave amplitude average on the 2 central rings was 0.19 mv, and b wave amplitude was 0.48 mV. Correlation between BCVA and central foveal thickness was established and found to be inversely correlated and statistically significant R: -0.48, r2: 0.21). No statistically significant correlation was found between any other parameters.
Conclusion: Best-corrected visual acuity mildly correlates (20%) with central foveal thickness.
REFERENCES
Charlotte W, Lardenoye A, Probst K, DeLint PJ, Rothova A. photoreceptor function in eyes with macular edema. Invest Ophthalmol Vis Sci 2000; 41: 4048-4053.
Bresnick GH. Diabetic maculopathy: a critical review highlighting diffuse macular edema. Ophthalmology 1983; 90:1301-1317.
Hee MR, CA Puliafito, JS Duker, E Reichel, JG Coker, JR Wilkins y cols. Topography of diabetic macular edema with optical coherence tomography. Ophthalmology 1998; 105: 360-370.
Nussenblatt RB, Kaufman SC, Palestine AG, Davis MD, Ferris FL. Macular thicknening and visual acuity. Ophthalmology 1987; 94:1134-1139.
Ryan S. Retina. Vol. 2, 3ª edición, 2001. p 1299.
Early Treatment Diabetic Retinopathy Study Research Group: Photocoagulation for diabetic macular edema, ETDRS report no 4. Int Ophthalmol Clin 1987; 27:265-272.
Early Treatment Diabetic Retinopathy Study Research Group: Photocoagulation for diabetic macular edema, ETDRS report no 1. Arch Opthalmol 1985; 103:1796-1806.
Huang D, Swanson EA, Lin CP y cols. Optical coherence tomography. Science 1991; 254:1178-1181.
Yang CS, Cheng CY, Lee FL, Hsu WM, Liu JH. Quantitative assessment of retinal thickness in diabetic patients with and without clinically significant macular edema using optical coherence tomography. Acta Ophthalmol Scand 2001; 79(3):266-70.
Massin P, Vicaut E, Haouchine B, Erginay A, Paques M, Gaudric A. Reproducibility of retinal mapping using optical coherence tomography. Arch Ophthalmol 2001; 119(8):1135-42.
Yamamoto S, Yamamoto T, Hayashi M, Takeuchi S. Morphological and functional analyses of diabetic macular edema by optical coherence tomography and multifocal electroretinograms. Graefes Arch Clin Exp Ophthalmol 2001; 239(2):96-101.
Hee MR, Puliafito CA, Wong C y cols. Quantitative assessment of macular edema with optical coherence tomography. Arch Ophthalmol 1995; 113:1019-29.
Sternberg P, Fitzke F, Finkelstein D. Cyclic macular edema. Am J Ophthalmol 1982; 94:664-669.
Weiner A, Christopoulos VA, Gussler CH y cols. Foveal cone function in nonproliferative diabetc retinopathy and macular edema. Invest Ophthalmol Vis Sci 1997; 38:1443-1449.
Shahidi M, Ogura Y, Blair NP, Rusin MM, Zeimer R. Retinal thickness analysis for quantitative assessment of diabetic macular edema. Arch Ophthalmol 1991; 109:1115-1119.
Talwar D, Sharma N, Pai A, Azad RV, Kohli A, Virdi PS. Contrast sensitivity following focal laser photocoagulation in clinically significant macular oedema due to diabetic retinopathy. Clin Experiment Ophthalmol 2001; 29(1):17-21.
Rutledge BK, Puliafito CA, Duker JS, Hee MR, Cox MS. Optical coherence tomography of macular lesions associated with optic nerve head pits. Ophthalmology 1996: 103:1047-1053.
Wilkins JR, Puliafito CA, Hee MR y coils. Characterization of epiretinal membranes using optical coherence tomography. Ophthalmology 1996; 103:2142-2151.
Hee MR, Puliafito CA, Wong C y cols. Optical coherence tomography of central serous chorioretinopathy. Am J Ophthalmol 1995; 120:65-74.
Hee MR, Baumal CR, Puliafito CA y cols. Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology 1996; 103:1260-1270.
Hee MR, Puliafito CA, Wong C y cols. Optical coherence tomography of macular holes. Ophthalmology 1995; 102:748-56.
Koozekanani D, Roberts C, Katz S, Herderick E. Intersession repeatibility of macular thickness measurements with the Humphrey 2000 OCT. IOVS 2000; 41:1486-1491.
Shirao Y, Kawasaki K. Electrical responses from diabetic retina. Prog Retinal Eye Res 1998; 17:59-76.
Bresnick GH, Korth K, Groo A, Palta M. Electroretinographic oscillatory potentials predict progression diabetic retinopathy. Arch Ophthalmol 1984; 102:1307-1311.
Gjotterberg M. The electroretinogram in diabetic retinopathy: a clinical study and a critical survey. Acta Ophthalmol 1974; 52:521-533.
Holopigian K, Greenstein VC, Seiple W, Hood DC, Carr RE. Evidence for photoreceptor changes in patients with diabetic retinopathy. Invest Ophthalmol Vis Sci 1997; 38:2355-2365.
Palmowski AM, Sutter EE, Fung W. Mapping of retinal function in diabetic retinopathy using the multifocal electroretinogram. Invest Ophthalmol Vis Sci 1997; 38:2586-2596.
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