2006, Number 4
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Rev Mex Oftalmol 2006; 80 (4)
Determinación de anticuerpos séricos contra proteínas de choque térmico en pacientes con glaucoma
Elizondo-Olascoaga C, Cancino-Díaz JC, Morales-González A
Language: Spanish
References: 18
Page: 175-179
PDF size: 156.36 Kb.
ABSTRACT
Purpose: To determine serum antibody levels for bacterial heat shock proteins 60 kd in patients with glaucoma and healthy subjects.
Methods: We performed comparative analysis of serum antibody levels for two different bacterial heat shock proteins 60k in 22 patients with chronic open angle glaucoma, 21 in normal-tension glaucoma and 22 healthy subjects using an indirect enzyme-linked immunosorbent assay.
Results: Patients with glaucoma had higher levels of antibodies against bacterial heat shock proteins compared with healthy subjects, this being statistically significant.
Conclusions: Mexican patients with glaucoma present higher levels of bacterial heat shock proteins. We require additional research in order to evaluate their relationship with the pathophysiologic mechanisms of glaucoma.
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