2006, Number 2
<< Back Next >>
Rev Mex Oftalmol 2006; 80 (2)
Resultados en endotropías no acomodativas tratadas con toxina botulínica
Toledo R, Saucedo A
Language: Spanish
References: 24
Page: 64-68
PDF size: 423.10 Kb.
ABSTRACT
Introduction: Perimuscular injection of Botulinum Toxin A is a therapy that may modify the eye alignment through a temporal muscle paralysis. Its utility has been documented in strabismus treatment, including non-accommodative esotropia patients. The aim of this study is to show the outcomes obtained in the treatment of non-accommodative esotropia.
Method: A chart review of those patients with non-accommodative esotropia younger than 24 months of age who were treated with perimuscular injection of Botulinum toxin A in both medial rectus were performed.
Results: We included 51 patients with non-accommodative esotropia with deviation greater than 20 DP (mean: 45 DP). We obtained the following results during a 12 month follow up period: eye alignment: 34.78%, residual esotropia ‹ 15 DP: 39.13%, residual esotropia › 15 DP: 17.39%, consecutive exotropia: 8.69%. One session of Botulinum toxin A injection was sufficient in 75.54% of the cases.
Conclusion. Botulinum toxin injection into bilateral medial rectus corrected 73.91% of non-accommodative esotropia cases. One application of Botulinum toxin corrected strabismus in most of the patients. Blepharoptosis was the most frequently seen complication. No changes in the refractive status were observed in any patient.
REFERENCES
Lopez Del Val LJ, Castro García A. Toxina botulínica. Aplicaciones terapéuticas. Masson SA, 2002, p.1-49, 75-77.
Scott AB. Botulinum toxin inyection into extraocular muscles as an alternative to strabismus surgery. Ophthalmology 1980; 87(10):1044-1049.
Nelson LB y cols. Congenital esotropia. Surv Ophthalmol 1987; 31:363.
Scott AB y cols. Botulinum treatment of childhood strabismus. Ophthalmology 1990; 97(11):1434-1438.
Editorial. Botulinum toxin management of essential infantile esotropia in children. Arch Ophthalmol 1997; 115:1458-1459.
McNeer KW y cols. Botulinum toxin management of essential infantile esotropia in children. Arch Ophthalmol 1997; 115:1411-1418.
McNeer KW y cols. Efficacy of botulinum toxin injection in infantile esotropia. Invest Ophthalmol Vis Sci 1991; 32:1241.
McNeer KV y col. Observations on simultaneous botulinum toxin injection in infantile esotropia. J Pediatr Ophthalmol Strabismus 1994; 31(4):214-219.
McNeer KW y cols. Botulinum toxin therapy for essential infantile esotropia in children. Arch Ophthalmol 1997; 116:701-702.
McNeer KV y cols. Management of essential infantile esotropia with botulinum toxin A: review and recommendations. J Pediatr Ophthalmol Strabismus 2000; 37(2):63-67.
Biglan AW y cols. Management of strabismus with botulinum a toxin. Ophthalmology 1989; 96(7):935-946.
Horgan SE y cols. The long-term use of botulinum toxin for adult strabismus. J Pediatr Ophthalmol Strabismus 1998; 35(1):9-16.
Tejedor J, Rodríguez JM. Early retreatment of infantile esotropia: comparison of reoperation and botulinum toxin. Br J Ophthalmol 1999; 83:783-787.
Holmes JM y col. Initial treatment outcome in chronic sixth nerve palsy. JAAPOS 2001; 5(6):370-376.
Kerr NC y cols. Botulinum toxin for sixth nerve palsies in children with brain tumors. JAAPOS 2001; 5(1):21-25.
Ruiz MF y cols. Botulinum treatment of infantile esotropia with abduction nystagmus. J Pediatr Ophthalmol Strabismus 2000; 37(4):196-205.
Kao LY y cols. Subtenon inyection of botulinum toxin for treatment of traumatic sixth nerve palsy. J Pediatr Ophthalmol Strabismus 2003; 40(1):27-30.
Han SH y cols. Effect of botulinum toxin a chemodenervation in sensory strabismus. J Pediatr Ophthalmol Strabismus 2001; 38(2):68-71.
Ing MR. Botulinum alignment for congenital esotropia. Ophthalmology 1993; 100(3):318-322.
Shauly Y y col. Clinical characteristics and long-term postoperative results of infantile esotropia. Am J Ophthalmol 1994; 117(2):183-189.
Tejedor J, Rodriguez JM. Retreatment of children after surgery for acquired esotropia: reoperation versus botulinum injection. Br J Ophthalmol 1998; 82:110-114.
Hiles DA y cols. Characteristics of infantile esotropia following early bimedial rectus recession. Arch Ophthalmol 1980; 98:697-703.
Birch EE y col. Why does early surgical alignment improve stereoacuity outcomes in infantile esotropia?. JAAPOS 2000; 4(1):10-14.
McNeer KW y cols. Iincidence of stereopsis after treatment of infantile esotropia with botulinum toxin A. J Pediatr Ophthalmol Strabismus 2003; 40(5):288-292.