2008, Number 2
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salud publica mex 2008; 50 (2)
Maternal chemoprophylaxis against group B Streptococcus colonization. The consequences of not adopting the international recommendation
Reyna-Figueroa J, Ortiz-Ibarra FJ, Pérez-Antonio B, Navarro-Godínez S, Casanova-Román G, García-Carrillo LE
Language: Spanish
References: 26
Page: 155-161
PDF size: 155.31 Kb.
ABSTRACT
Objective. To know the criteria which determine the chemoprophylaxis on pregnant women colonized by Streptococcus agalactiae (GBS) and the impact in our environment.
Material and Methods. A retrospective analysis, identifying pregnant women with isolation of Streptococcus agalactiae on screening cultures, cervical swabs and urine culture. Two groups were analyzed, group 1 received chemoprophylaxis, and group 2 without chemoprophylaxis. Chi square was used to asses the difference between proportions. Chi square approximation to Poisson distribution was used to compare the means of neonatal infection.
Results. A total of 274 cultures were reported with GBS isolation, on 261 patients; 165 (60.2%) cervical swabs, 109 (39.7%) urine culture and 13 patients from 274 (4.7%) had positive culture on both specimens. Of this 261 patients, 53 (5.6%) received chemoprophylaxis during labor (p‹0.05). The CDC criteria were followed accuracy on 29.2%.
Conclusions. There have not been established criteria for screening colonization by GBS in Mexican pregnant women.
REFERENCES
Allardice JG, Baskett TF, Seshia MM, Bowman N, Malazdrewicz R. Perinatal group B streptococcal colonization and infection. Am J Obstet Gynecol 1982; 142: 617-620.
Schuchat A, Wenger JD. Epidemiology of group B streptococcal disease. Risk factors, prevention strategies, and vaccine development. Epidemiol Rev 1994; 16: 374-402.
Schrag SJ, Zywicki S, Farley MM, Reingold AL, Harrison LH, Lefkowitz, LB, Hadler JL, Danila RC, Paul R S. Group B Streptococcal disease in the era of intrapartum antibiotic prophylaxis. N Engl J Med 2000; 342: 15-20.
Lloyd DJ, Reid TM. Group B streptococcal infection in the newborn. Criteria for early detection and treatment. Acta Paediatr Scand 1976; 65: 585-591.
Allen UD, Navas L, King SM. Effectiveness of intrapartum penicillin prophylaxis in preventing early-onset group B streptococcal infection: results of a meta-analysis. CMAJ 1993; 149: 1659-1665.
Ohlsson A, Myhr TL. Intrapartum chemoprophylaxis of perinatal group B streptococcal infections: a critical review of randomized controlled trials. Am J Obstet Gynecol 1994; 170: 910-917.
Centers for Disease Control and Prevention. Prevention of Perinatal Group B Streptococcal Disease. MMWR 2002; 51 (No. RR-11).
Eickhoff T, Klein J, Daly A, Ingall D, Finland M. Neonatal sepsis and other infections due to group B beta hemolytic streptococci. N Engl J Med 1964; 271: 1221-1228.
Society of Obstetricians and Gynaecologists of Canada and Canadian Paediatrics Society. National consensus statement on the prevention of early onset group B streptococcal infections in the newborn. J Soc Obstet Gynaecol Can 1994;16(10):2271-2278.
Canadian Paediatric Society, Infectious Diseases and Immunization Committee. The prevention of early-onset group B streptococcal infections in the newborn [consensus statement]. Can J Infect Dis 1994; 5(6): 251-256.
Davies HD, Adair EC, Schuchat A, Low E, Sauve R, McGeer A. Canada physicians’ prevention practices and incidence of neonatal group B streptococcal disease in 2 Canadian regions. CMAJ 2001; 164: 20.
Collado ML, Kretschmer RR, Becker I, Guzmán A, Gallardo L, Lepe CM. Colonization of Mexican pregnant women with group B Streptococcus, J Infect Dis 1981; 143: 134.
Solórzano SF, Echaniz AG, Conde GCJ, Calderón JE, Arredondo GJL, Beltrán ZM. Cervicovaginal infection with Group B streptococci among pregnant Mexican women. J Infect Dis 1989; 159:1003-1004.
González PA, Ortiz ZMC, Mota VR. Serotypes and antimicrobial susceptibility of group B Streptococcus isolated from pregnant women in Mexico. Rev Latinoam Microbiol 2002; 44: 133-136.
Palacios CG, Eskew KE, Solórzano SF, Mattingly JS, Decreced capacity for type- specific antigen synthesis accounts for high prevalence of nontypeable strains of group B streptococci in Mexico. J Clin Microbiol 1997; 35: 2923-2926.
Ortiz IFJ, Reyna FJ, Casanova RG, Villegas MMI. Streptococcus agalactiae: la importancia de la quimioprofilaxis en la prevención perinatal. Enf Infec y Microbiol 2004; 24: 120-124.
Instituto Nacional de Perinatología. Anuario estadístico 2001. México: INPer.
Instituto Nacional de Perinatología; Anuario estadístico 2002. México: INPer.
Instituto Nacional de Perinatología; Anuario estadístico 2003. México: INPer.
C, Jr. Strategies for the prevention of early-onset neonatal group B streptococcal sepsis: a decision analysis. Obstet Gynecol 1994; 83(4): 483-494.
Revised guidelines for prevention of early-onset group B streptococcal (GBS) infection. American Academy of Pediatrics Committee on Infectious Diseases and Committee on Fetus and Newborn. Pediatrics 1997; 99(3): 489-496.
Prevention of perinatal group B streptococcal disease: a public health perspective. Centers for Disease Control and Prevention. Morb Mortal Wkly Rep 1996; 45(RR-7): 1-24.
Reyna FJ, Ortiz IFJ, Beltrán ZM, Villegas GG, Limón RAE. Riesgo de infección neonatal temprana en recién nacidos hijos de mujeres embarazadas colonizadas con Streptococcus agalactiae Serotipo III Rev Enf Infec Ped 2005;73:13-17.
Fena YC, Clemens DJ, Azimi HP, Regan JA, Capsular polysaccharide types of Group B Streptococcal isolates from neonates with early-onset systemic infection. J Infect Dis 1998; 177: 790-792.
Weeks JW, Myers SR, Laser L, Goldsmith J, Watkins C, Gall SA. Persistence of penicillin G in pregnant group B Streptococcus carriers. Obstet Gynecol 1997;90: 2040-2243.
Narcio RML, Solórzano SF, Arredondo GJL, Calderón JE, Beltrán ZM. Etiología de la infeccón cervicovaginal en pacientes embarazadas y no embarazadas. Ginecol Obstet Mex 1989; 57:41-46.