Conde-González CJ, Valdespino JL, Juárez-Figueroa LA, Palma O, Olamendi-Portugal M, Olaiz-Fernández G, Sepúlveda J

Language: Spanish
References: 24
Page: 412-420
PDF size: 210.73 Kb.

ABSTRACT

Objective. To measure for the first time in a population based study the prevalence of antibodies against Treponema pallidum among the Mexican adult population and correlates of infection. Materials and Methods. This study was derived from the Mexican National Health Survey carried out in 2000. Anti-T. pallidum seroprevalence was determined according to an algorithm based on a set of treponemic and non-treponemic serological tests for 12 010 sera randomly selected from participating women and men 20 years and older. A statistical analysis was applied to identify seropositivity associated variables. Results. Anti-T. pallidum seroprevalence was 3.1% (CI95% 2.5-3.7). Population characteristics significantly related to infection exposure were: older age (OR 3.3), being male (OR 1.3), inhabiting the southern region of the country (OR 1.7), having a regular partner not being married (OR 2.7) or being a widow (OR 1.8), early age at sexual debut (OR 6.3), and for women, having had still births (OR 1.8) and not using the condom as a contraceptive measure (OR 14.1). Conclusions. Results obtained show that exposure to T. pallidum infection among Mexican adults is at present a true public health problem, unknown until now. Factors associated with seropositivity were those expected considering the epidemiology of sexually transmitted infections. Health authorities must reinforce the surveillance and diagnosis of syphilis in Mexico to help prevent and control the transmission of the etiologic agent.

REFERENCES

1. Holmes KK, Sparling PF, Mardh PA, Lemon SM, Stamm WE, Piot P, et al. Sexually transmitted diseases. 3rd ed. New York: McGraw-Hill, 1999.

2. Larsen SA, Pope V, Johnson RE, Kennedy EJ. A manual of tests for syphilis. 9th ed. Washington, DC: American Public Health Association, 1998.

3. Sparling PF. Natural history of syphilis. In: Holmes KK, Sparling PF, Mardh PA, Lemon SM, Stamm WE, Piot P, et al., eds. Sexually transmitted diseases. 3rd New York: McGraw-Hill, 1999.

4. Conde-González CJ. Enfermedades de transmisión sexual. Libro B-4, PAC- Infecto-1. México, DF: Intersistemas, 1999.

5. Anuarios de morbilidad 2001-2005, Secretaría de Salud, México. Disponible en: http://www.dgepi.salud.mx. .

6. Zamilpa-Mejía LG, Uribe-Salas F, Juárez-Figueroa L, Calderón-Jaimes E, Conde-González CJ. Prevalencia y factores asociados para sífilis y herpes genital en dos grupos de población femenina. Salud Publica Mex 2003;45 supl5:S617-S623.

7. Uribe-Salas F, Del Rio-Chiriboga C, Conde-González CJ, Juárez-Figueroa L, Uribe-Zuñiga P, Calderón-Jaimes E, et al. Prevalence, incidence and determinants of syphilis in female commercial sex workers in Mexico City. Sex Transm Dis 1996;23:120-126.

8. Valdespino-Gómez JL, García-García ML, del Río-Chiriboga C, Cruz-Palacios C, Loo-Méndez E, López-Sotelo A. Las enfermedades de transmisión sexual y la epidemia de VIH/SIDA. Salud Publica Mex 1995;37:549-555.

9. Conde-González CJ. Perspectiva del estudio de las infecciones transmitidas sexualmente en la República Mexicana. Enf Infec y Microbiol 2000;20:96-101.

10. Juárez-Figueroa LA, Meléndez-Betancourt LA, Conde-González CJ. Hallazgo de sífilis a término del embarazo en mujeres de Cuernavaca, Mor. Rev Invest Clin (Mex) 2001;53:375-377.

11. Hernández-Trejo M, Hernández-Prado B, Uribe-Salas F, Juárez-Figueroa L, Conde-González CJ. Sífilis materna y congénita en dos hospitales mexicanos: evaluación de una prueba diagnóstica rápida. Rev Invest Clin (Mex) 2006;58:119-125.

12. Frías SJA, García VJL. Reporte de resultados de 9,809 exámenes de VDRL realizados en el Hospital Central Militar en 1996. Rev Sanid Milit Méx 1997;6:251-254.

13. Pita-Ramírez L, Torres-Ortiz GE. Prevalencia de anticuerpos virales y reaginas luéticas en donadores de sangre de un hospital. Rev Invest Clin 1997;49:475-480.

14. Beltrami JF, Weinstock HS, Berman SM, Swint EB, Fenton KA, Lindstrom HA. Primary and secondary syphilis-United States, 2003-2004. MMWR 2006;55:269-273.

15. Olaiz G, Rojas R, Barquera S, Shamah T, Aguilar C, Cravioto P, et al. Encuesta Nacional de Salud 2000. Tomo 2, La salud de los adultos. Cuernavaca, Morelos, México: Instituto Nacional de Salud Pública, 2003.

16. Young H. Guidelines for serological testing for syphilis. Sex Transm Inf 2000;76:403-405.

17. Ley de Información Estadística y Geográfica. Diario Oficial de la Federación. México, Diciembre 30, 1980.

18. Peterman TA, Heffelfinger JD, Swint EB, Groseclose SL. The changing epidemiology of syphilis. Sex Transm Dis 2005;32(Suppl 10):S4-S10.

19. Ciesielski C, Kahn RH, Taylor M, Gallagher K, Prescott LJ, Arrowsmith S. Control of syphilis outbreaks in men who have sex with men: the role of screening in nonmedical settings. Sex Transm Dis 2005;32(Suppl 10):S37-S42.

20. Baltasar-Reyes MC, Rivera-Rivera L, Cruz-Valdez A, Hernández-Girón CA. Prevalencia de infecciones transmitidas sexualmente y factores de riesgo asociados entre trabajadoras del sexo comercial en Cuautla, Morelos. Ginecol Obstet Mex 2005;73:36-47.

21. Uribe-Salas F, Conde-González CJ, Juárez-Figueroa L, Hernández-Castellanos A. Sociodemographic dynamics and sexually transmitted infections in female sex workers at the Mexican-Guatemalan border. Sex Transm Dis 2003;30:266-271.

22. Hernández-Girón C, Uribe-Salas F, Conde-González C, Cruz-Valdez A, Juárez-Figueroa L, Uribe-Zúñiga P, et al. Seroprevalencias a diversos virus y características sociodemográficas en mujeres que buscan detectarse VIH. Rev Invest Clin (Mex) 1997;49:5-13.

23. Noyola DE, Malacara-Alfaro O, Lima-Rogel V, Torres-Montes A. Seroprevalencia de sífilis en mujeres embarazadas en San Luis Potosí. Salud Publica Mex 2006;48:151-154.

24. Sombié I, Meda N, Cartoux M, Tiendrébéogo S, Ouangré A, Yaro S, et al. Seroprevalence of syphilis among women attending urban antenatal clinics in Burkina Faso, 1995-8. Sex Transm Inf 2000;76:314-316.