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Instituto Nacional de Salud Pública

2007, Number S3

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salud publica mex 2007; 49 (S3)

C-reactive protein concentrations in Mexican men and women: high prevalence of a cardiovascular risk factor

Flores M, Barquera S, Carrión C, Rojas R, Villalpando S, Olaiz-Fernández G, González-Villalpando C

Language: Spanish
References: 38
Page: 348-360
PDF size: 283.33 Kb.


ABSTRACT

Objective. To examine the distribution and correlates of C-reactive protein (CRP) concentrations in Mexican adults. Material and Methods. Data was analyzed from 2 194 Mexican adults who participated in the 2000 National Health Survey (ENSA-2000). CRP concentrations were measured with a high-sensitivity assay. Information on sociodemographic characteristics, chronic disease and habits was obtained. Fasting blood glucose, blood pressure, weight, height and waist circumference were measured. Results. A total of 730 men and 1 464 non-pregnant women were studied. Mean age was 38.3±15.2 years. CRP concentrations ranged from 0.19 to 255 mg/L (median: 2.26; interquartile range (FIR): 0.96, 5.83 mg/L). CRP concentrations were higher in women (median: 2.86; IR: 1.11, 6.68 mg/L) than men (median: 1.63; IR: 0.8, 3.87 mg/L; p‹0.001). Thirty-one percent of individuals (35.1% women, 23.3% men) had CRP concentrations ›3.0-10 mg/L. Multivariate probit regression analysis showed that age, BMI, waist circumference, diabetes, microalbuminuria and use of oral contraceptives were positively associated with CRP concentrations ›1 mg/L. Male gender and moderate alcohol consumption were negatively associated with CRP concentrations ›3 mg/L (p‹0.05). Conclusion. There is a high prevalence of CRP concentrations in the range of ›3.0-10 mg/l in Mexican adults, indicating a considerable proportion of individuals at risk for cardiovascular disease, independent of other risk factors.


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