Remolina SM

Language: Spanish
References: 38
Page: 58-67
PDF size: 124.07 Kb.

ABSTRACT

We present an original prospective retrolective clinical study. In this work data is presented in a quantitative manner about drugs employed for sedation and analgesia in a continuous intravenous form, combined or sequentially for all patients cared for in a five-year period in the Medica Sur ICU. We included 1,507 patients admitted to the Medica Sur ICU. About half corresponds to each gender, half to surgical or medical cases and the mean age was 53 years (10-97). Received one or more study drugs 1,165 (77%) patients; surgical cases (SC) 62% and 37% medical cases (MC). By group 480 SC patients with mechanical ventilation (MV) and 362 (72%) received one or more drugs for sedation/analgesia (SA), those SC without MV 357; 337 received SA (94%). MC group with 290 cases in total; 278 (95%) received SA, the rest with 380 MC without MV and only 49% received any of the study drugs. Most interesting results show an increase throughout the years of the proportion of patients that received fentanyl, propofol and dexmedetomidine. There was a reduction of the proportion of patients receiving midazolam. In contrast we note an increase in the mean and total doses employed of dexmedetomidine and midazolam and lower mean and total daily doses of fentanyl and propofol. In conclusion lesser doses are used of some drugs in comparison to larger doses of dexmedetomidine used in combination. A smaller proportion of patients received midazolam in comparison to the first years with larger mean and total doses.

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