Gelman S

Language: English
References: 14
Page: 45-47
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INCIDENCE OF POSTOPERATIVE HEPATIC COMPLICATIONS

Surgical stress, particularly laparotomy, in patients with liver disease carries high mortality rate. For example, a 30 day mortality rate after laparotomy with liver biopsy, in patients with liver disease was approaching 30%. The presence of acute viral hepatitis, alcoholic hepatitis, ascites, or prolongation in prothrombin time by more than 2.5 seconds increased 30 day mortality to 85-95%. More recent studies suggest an improvement: overall perioperative 30-day mortality was reported as 11.6%; perioperative complication rate remains at the level of 30%. Factors associated with perioperative complications and mortality includes male gender, the presence of ascites, diagnosis of cirrhosis, an elevated creatinine concentration, chronic obstructive pulmonary disease, perioperative infection, upper gastrointestinal bleeding, presence of intraoperative hypotension and some others.

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