Morales SE, Ledesrna MN

Language: English/Spanish
References: 24
Page: 159-162
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Text Extraction

A three year old male English Mastiff of approximately 60 kg of weight was taken to the veterinaria for an examination. It showed progressive paralysis in the hindlimbs, fecal and urinary incontinence and haematuria. The general physical examination of the dog showed normal limits. Nevertheless, the neurological examination revealed paresis, ataxia with uneven hindlimbs and hidlimbs hyperreflexia. Clinical, signs suggested an injury in the spinal cord located in the lumbar segment. Due to progressive suffering and inefficient treatment, the patient was eutanized and a compIete necropsy was practiced. No significant injuries in organs or tissues were found. A medullar compression was not present. The histologic examination of the lumbar spine revealed symmetrical degeneration of axons and myelin in the lateral and ventromedial white substance of the spinal cord at the L5 level, and asymmetrical degeneration of axons and myelin in the lateral and ventromedial white substance extended to the right side at the L6 level. Pathological changes were similar to the ones present in old German Shepherd dogs with degenerative myelopathy.

REFERENCES

1. Averill, D.R.: Degenerative rnyelopathy in the aging German Shepherd dog: Clinical and pathologic findings. J. Am. vet. med. Ass., 162: 1045-1051 (1973).

2. Bichsel, P., Vandevelde, M., Lang, J. and Kull-Hachler, S.: Degenerative myelopathy in a family of Siberian Husky dogs. J. Am. vet. med. Ass., 183: 998-1000 (1983).

3. Braund, K.G.: Hip dysplasia and degenerative myelopathy: Marking the distinction in dogs. Vet. Med., 82: 782-789 (1987).

4. Braund, K.G.: and Vandevelde, M.: German Shepherd dog myelopathy. A morphological and morphometric study. Am. J. vet. Res., 39: 1309-1315 (1978).

5. Catcott, E.J.: Canine Medicine. 4th ed. American Veterinary Publications, Santa Barbara, California, 1979.

6. Chisman, C.L.: Problemas Neurológicos en Pequeñas Especies. 2a ed. CECSA, México, D.F., 1987.

7. Hayes, M.A., Creighton, R.S., Boysen, B.G. and Holfeld, N.: Acute necrotizing myelopathy from nucleus pulposus embolism in dogs with intervertebral disk degeneration. J. Am. vet. med. Ass., 173: 289-295 (1978).

8. Hoerlein, B.F.: Canine Neurology. Diagnosis and Treatment. 3rd ed. W.B. Saunders, Philadelphia, 1987.

9. Longhofer, S.L., Duncan, I.D. and Messing, A.: A degenerative myelopathy in young German Shepherd dogs. J. Small Anim. Pract, 31: 199-203 (1990).

10. Mayberry, K. and Carithers, R.W.: Degenerative myelopathy in the German Shepherd. Iowa State Univ. Vet., 37: 18-28 (1975).

11. 1 1. Romatowsky, J.: Degenerative myelopathy in a German Shepherd. Mod. vet. Pract., 65: 535-537 (1984).

12. Wakman, F.J., Clemmons, R.M. and Hinriech, D.J.: Progressive myelopathy in older German Shepherd dogs. II Presence of circulating suppressor cells. J. Immunol., 124: 1216-1222 (1980).

13. Averill, D.R.: Degenerative rnyelopathy in the aging German Shepherd dog: Clinical and pathologic findings. J. Am. vet. med. Ass., 162: 1045-1051 (1973).

14. Bichsel, P., Vandevelde, M., Lang, J. and Kull-Hachler, S.: Degenerative myelopathy in a family of Siberian Husky dogs. J. Am. vet. med. Ass., 183: 998-1000 (1983).

15. Braund, K.G.: Hip dysplasia and degenerative myelopathy: Marking the distinction in dogs. Vet. Med., 82: 782-789 (1987).

16. Braund, K.G.: and Vandevelde, M.: German Shepherd dog myelopathy. A morphological and morphometric study. Am. J. vet. Res., 39: 1309-1315 (1978).

17. Catcott, E.J.: Canine Medicine. 4th ed. American Veterinary Publications, Santa Barbara, California, 1979.

18. Chisman, C.L.: Problemas Neurológicos en Pequeñas Especies. 2a ed. CECSA, México, D.F., 1987.

19. Hayes, M.A., Creighton, R.S., Boysen, B.G. and Holfeld, N.: Acute necrotizing myelopathy from nucleus pulposus embolism in dogs with intervertebral disk degeneration. J. Am. vet. med. Ass., 173: 289-295 (1978).

20. Hoerlein, B.F.: Canine Neurology. Diagnosis and Treatment. 3rd ed. W.B. Saunders, Philadelphia, 1987.

21. Longhofer, S.L., Duncan, I.D. and Messing, A.: A degenerative myelopathy in young German Shepherd dogs. J. Small Anim. Pract, 31: 199-203 (1990).

22. Mayberry, K. and Carithers, R.W.: Degenerative myelopathy in the German Shepherd. Iowa State Univ. Vet., 37: 18-28 (1975).

23. Romatowsky, J.: Degenerative myelopathy in a German Shepherd. Mod. vet. Pract., 65: 535-537 (1984).

24. Wakman, F.J., Clemmons, R.M. and Hinriech, D.J.: Progressive myelopathy in older German Shepherd dogs. II Presence of circulating suppressor cells. J. Immunol., 124: 1216-1222 (1980).