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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2006, Number 1

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Rev Biomed 2006; 17 (1)

Paralytic poisoning syndrome due to the shellfish consumption

Hernández-Orozco ML, Gárate-Lizárraga I

Language: Spanish
References: 101
Page: 45-60
PDF size: 317.60 Kb.


ABSTRACT

Paralytic shellfish poisoning (PSP) is a neurotoxic syndrome related to shellfish containing saxitoxin (STX) and its more than 26 analogues. Toxins are produced by several species of dinoflagellates from the genera Alexandrium, Pyrodinium bahamense var. compressum, Gymnodinium catenatum and some species of cianobacteria. The symptoms caused by the saxitoxin and its derivatives mainly attack the nervous system. Diagnosis of this paralytic shellfish poisoning must be done by means of mouse bioassay or isolating the toxin producing organisms. There is no antidote and the treatment for intoxication is symptomatic, focused on maintaining the ventilator mechanism. In our country, toxic episodes have been observed in both littoral shores; however, there are few monitoring programs. The incidence of toxic episodes as well as the presence of paralytic toxins has increased and they have been reported in new areas where they were previously uncommon. For this reason it is important to divulge information about this kind of poisoning since it represents a potential danger to human health.


REFERENCES

  1. 1.- Lehane L. Paralytic Shellfish Poisoning: A review. National Office of Animal and Plant Health, Agriculture, Fisheries and Forestry - Australia, Canberra; 2000.

  2. 2.- Anderson DM, Andersen P, Bricelj VM, Cullen JJ, Rensel JE. Monitoring and Management Strategies for Harmful Algal Blooms in Coastal Waters. APEC · 201-MF-01.1. Asia Pacific Economic Program, Singapore, an Intergovernmental Oceanographic Commission Technical Series Nº 59, Paris 2001.

  3. 3.- Hallegraeff GM. A review of harmful algal blooms and their apparent global increase. Phycologia 1993; 32: 79-99.

  4. 4.- Van Dolah FM. Marine algal toxins: origins, health effects, and their increased occurrence. Environ Health Perspect. 2000; 108 Suppl 1:133-41.

  5. 5.- Brett MM. Food poisoning associate with biotoxins and shellfish. Curr Opin Infect Dis 2003; 16: 461-5.

  6. 6.- Lagos N. Micoalgal blooms: a global issue with negative impact in Chile. Biol Res 1998; 31: 375-86.

  7. 7.- Rhodes FA, Mills CG, Popei K. Paralytic shellfish poisoning in Papua New Guinea. P N G Med J 1975;18: 197-202.

  8. 8.- Popkiss ME, Horstman DA, Harpur D. Paralytic shellfish poisoning. A report of 17 cases in Cape Town. Afr Med J 1979; 55: 1017-23.

  9. 9.- Tan CT, Lee EJ. Paralytic shellfish poisoning in Singapore. Ann Acad Med Singapore 1986; 15: 77-9

  10. 10.- Shumway SE, Barter J, Sherman-Caswell S. Auditing the impact of toxic algal blooms on oysters. Environ Audit 1990; 2: 41-56.

  11. 11.- Shumway SE, Cembella AD. The impact of toxic algae on scallop culture and fisheries. Rev Fish Sci 1993; 1: 121-50.

  12. 12.- Parrilla-Cerrillo MC, Vázquez-Castellanos JL, Saldate-Castañeda EO, Nava-Fernández LM. Brotes de toxiinfecciones alimentarias de origen microbiano y parasitario. Salud Pública Mex 1993; 35: 456-63.

  13. 13.- Fleming LE, Katz D, Bean JA, Hammond R. Epidemiology of seafood poisoning. En Hui YH, Kitts D, Stanfield PS editores: Foodborne Disease Handbook Volume 4: Seafood and Environmental Toxins. New York: Marcel Dekker Inc; 2000. p. 297-310.

  14. 14.- Kao CY. Paralytic shellfish Poisoning. En Falconer I, editor. Algal Toxins in Seafood and Drinking Water. London: Academic Press; 1993. p. 75-86.

  15. 15.- Holmes MJ, Teo SL. Toxic marine dinoflagellates in Singapore waters that cause seafood poisonings. Clin Exp Pharmacol Physiol 2002; 29:829-36.

  16. 16.- Sobel J, Painter J. Illnesses caused by marine toxins. Clin Infect Dis 2005; 41: 1290-6.

  17. 17.- Ade P, Funari E, Poletti R. Risk to human health associated with marine toxic algae. Ann Ist Super Sanita 2003; 39:53-68.

  18. 18.- Gárate-Lizárraga I. Florecimientos algales nocivos. En: Anguas-Vélez B. H. (ed.) Perspectivas para el desarrollo acuacultural del sistema lagunar de Bahía Magdalena-Almejas, B.C.S., México: Comité Editorial del IPN; 2005. p. 41-48.

  19. 19.- Gómez-Aguirre S, Santoyo-Reyes H. Plancton de lagunas costeras: XI Transporte en tres estuarios del noroeste de México (noviembre l973). Rev Lat Amer Microbiol 1975; 17: 175-83.

  20. 20.- Licea-Durán S, Gómez-Aguirre S, Cortés-Altamirano R, Gómez S. Notas sobre algunos florecimientos algales y la presencia de especies tóxicas en cinco localidades del Pacífico Mexicano (1996-1999). En: Tresierra-Aguilar AE, Culquichicón-Malpica ZG (editores). VIII Congreso Latinoamericano sobre Ciencias del Mar (COLACMAR), 17-21 de octubre de 1999. Libro de resúmenes ampliados, T. 1. Trujillo -Perú. P335-7.

  21. 21.- Hernández-Becerril DU. Species of the planktonic diatom genus Pseudonitzscia of the Pacific coast of Mexico. Hidrobiologia 1992; 379: 77-84.

  22. 22.- Okolodkov Y, Gárate-Lizárraga I. An Annotated checklist of marine dinoflagellate (Dinophyceae) from de Mexican Pacific. Acta Bot Mex 2006; 74:1-154.

  23. 23.- Licea-Durán S, Zamudio ME, Luna R, Soto J. Free-living dinoflagellates in the southern Gulf of México: Report of data (1979-2002). Phycol Res 2004; 52: 419-28.

  24. 24.- Hernández-Becerril DU, Almazán-Becerril A. Especies de dinoflagelados del género Gambierdiscus (Dinophyceae) del Mar Caribe mexicano. Rev Biol Trop 2004; 52 (Suppl.1):77-87.

  25. 25.- Luckas B, Dahlmann J, Erler K, Gerdts G, Wasmund N, Hummert C. Hansen PD. Overview of key phytoplankton toxins and their recent occurrence in the North and Baltic Seas. Environ Toxicol 2005; 20:1-17.

  26. 26.- Rappala J, Robertson A, Negri AP, Berg KA, Tuomi P, Lyra C, et al. First report of saxitoxin in Finnish lakes and possible associated effects on human health. Environ Toxicol 2005; 20: 331-40.

  27. 27.- Blanco-Pérez J. Episodios nocivos por fitoplancton. En Maeda-Martínez AN. editor. Los Moluscos Pectínidos de Iberoamérica: Ciencia y Acuicultura. México: Editorial Limusa; 2001. p. 285-324.

  28. 28.- Landsber JH. The Effects of Harmful Algal Blooms on Aquatic Organism. Rev Fish Sci 2002; 10:113-390.

  29. 29.- Acres J, Gray J. Paralytic shellfish poisoning. Can Med Assoc J 1978; 119:1195-7.

  30. 30.- Mata L, Abarca G, Marranghello L, Viquez R. Paralytic shellfish poisoning by Spondylus calcifer contaminated with Pyrodinium bahamense, Costa Rica 1989-1990. Instituto de Investigaciones en Salud (INISA), Universidad de Costa Rica.

  31. 31.- Hallegraeff GM. Harmful algal blooms: a global overview. En: Hallegraeff GM, Anderson DM, Cembella A, Editores. Manual on Harmful Marine Microalgae. Paris: UNESCO; 2003. p. 25-49.

  32. 32.- Chou HN, Chung YC, Chen CY. Evidence of paralytic shellfish poisoning toxin in milkfish in South Taiwan. Food Additives and Contaminants 2003; 20; 560-6.

  33. 33.- Goonetilleke A, Harris JB. Envenomation and consumption of poisonous seafood. J Neurol Neurosurg Psychiatry 2002; 73: 103-9.

  34. 34.- Bricelj MV, Shumway SE. Paralytic shellfish toxins in bivalve mollusks: occurrence, transfer kinetic, and biotransformation. Rev Fish Sci 1998; 6: 315-83.

  35. 35.- Mons MN, Van Egmond HP, Speijers GJA. Paralytic shellfish poisoning: A review. RIVM Report 388802 005. June 1998.

  36. 36.- Kulagina NV, O'Shaughnessy TJ, Ma W, Ramsdell JS, Pancrazio JJ. Pharmacological effects of the marine toxins, brevetoxin and saxiton, on murine frontal cortex neuronal networks. Toxicon 2004; 42:669-76.

  37. 37.- Stafford RG, Hines HB. Urinary elimination of saxitoxin after intravenous injection. Toxicon 1995; 53:1501-10.

  38. 38.- Andrinolo D, Michea LF, Lagos N. Toxic effects, pharmacokinetics and clearance of saxitoxin, a component of paralytic shellfish poison (PSP), in cats. Toxicon 1999; 37: 447-64.

  39. 39.- Shimizu Y. Chemistry and Mechanism of Action. En: Botana L, Dekker M, editores. Seafood and Freswater toxins Pharmacology, Phisiology, and Deteccion. Marcel Dekker Inc. New York: 2000, p 151-72.

  40. 40.- Schantz EJ. Chemistry and biology of saxitoxin and related toxins. Ann N Y Acad Sci 1986; 47: 15-23.

  41. 41.- Norma Oficial Mexicana de Emergencia, NOM-EM-005-SSA1-2001, Salud Ambiental. Especificaciones sanitarias para el control de los moluscos bivalvos expuestos a la marea roja. Criterios para proteger la salud de la población.

  42. 42.- Hungerford JM. Committee on Natural Toxins and Food Allergens. Marine and freshwater toxins. JAOAC Int 2005; 88:299-313.

  43. 43.- Kerr DS, Briggs DM, Saba HI. A neurophysiological method of rapid detection and analysis of marine algal toxins. Toxicon 1999; 37: 1803-25.

  44. 44.- Sar EA, Ferrario ME, Reguera B editores: Floraciones Algales Nocivas en el Cono Sur Americano. Madrid: Instituto Español de Oceanografía; 2002.

  45. 45.- Van Egmond HP, Jonker KM, Poelman M, Scherpenisse P, Stern AG, Wezenbeek P, Bergwerff AA, Van den Top HJ. Proeficiency studies on the determination of paralytic shellfish poisoning toxins in shellfish. Food Addit Contam. 2004; 21: 331-40.

  46. 46.- Vélez P, Sierralta J, Alcayaga C, Fonseca M, Loyola H, Johns DC, et al. A functional assay for paralytic shellfish toxins that uses recombinant sodium channels. Toxicon 2001; 39: 929-35.

  47. 47.- Louzao MC, Vieytes MR, Baptista de Sousa JM, Leira F, Botana LM. A fluorimetric method based on changes in membrane potential for screening paralytic shellfish toxins in mussels. Anal Biochem 2001; 289: 246-50.

  48. 48.- Powell CL, Doucette GJ. A receptor binding assay for paralytic shellfish poisoning toxins: recent advances and applications. Nat Toxins. 1999; 7: 393-400.

  49. 49.- Usleber E, Dietrich R, Burk C, Schneider E, Martbauer E. Immunoassay methods for paralytic shellfish posoning toxins. J AOAC Int. 2001; 84:1649-56.

  50. 50.- Laycock MV, Kralovec J, Richards R. some in vitro chemical interconversions of paralytic shellfish poisoning (PSP) toxins useful in the preparation of analytical standards. J Mar Biotechnol 1995; 3:121-5.

  51. 51.- Wu JY, Zheng L, Wang JH. Contamination of shellfish from Shangai seafood markets with paralytic shellfish poisoning and diarrhetic shellfish poisoning toxins determined by mouse bioassay and HPLC. Food Additives and Contaminats 2005; 22: 647-51.

  52. 52.- Okumura M, Tsuzuki H, Tomita B. A rapid detection meted for paralytic shellfish poisoning toxins by cell bioassay. Toxicon 2005; 46: 93-8.

  53. 53.- Kim CJ, Kim CH, Sako Y. Development of molecular identification method for genus Alexandrium (Dinophyceae) using whole-cell FISH. Marien Biotechnology 2005; 7: 215-22.

  54. 54.- Position of the American Dietetic Association: Food and water safety. J Am Diet Assoc. 2003; 103: 1203-18.

  55. 55.- Lipp EK, Rose JB. The role of seafood in foodborne disease in the United States of America. Rev Sci Tech. 1997; 16: 620-40.

  56. 56.- Geraci JR, Anderson DM, Timperi RJ, St. Aubin DJ, Early GA, Prescott JH, et al. Humpback whales fatally poisoned by dinoflagellate toxin. Can J Fish Res Aquat Sci 1989; 46: 1895-8.

  57. 57.- Backer LC, Flemming LE, Rowan AD, Baden DG. Epidemiology, public health and human diseases associated with harmful marine algae. En: Hallegraeff GM, Anderson DM, Cembella A, Editores. Manual on Harmful Marine Microalgae. Paris: UNESCO; 2003. p. 723-749.

  58. 58.- Fleming LE, Baden D. Florida Red Tide and Human Health: Background. NIEHS Marine and Freshwater Biomedical Center, University of Miami 1999. (avalaible from: URL:htpp://www.redtide.whoi.edu/hab/illness/floridaredtide.html)

  59. 59.- Rodrigue DC, Tzel RA, Hall S, de Porras E, Velásquez OH, Tauxe RV, et al. Letal paralytic shellfish poisoning in Guatemala. Am J Trop Med Hyg 1990; 42: 267-71.

  60. 60.- Gessner BD, Middaugh JP. Paralytic shellfish poisoning in Alaska: a 20-year retrospective analysis. Am J Epidemiol 1995; 141:766-70.

  61. 61.- Gessner BD, Schloss M. A population-based study of paralytic shellfish poisoning in Alaska. Alaska Med 1996; 38: 54-68.

  62. 62.- De la Garza-Aguilar J. Intoxicación alimentaria por ingestión de mariscos contaminados. Salud Pública Mex 1983; 25: 145-50.

  63. 63.- Mee LD, Espinosa M, Diaz G. Paralytic Shellfish Poisoning with a Gymnodinium catenatum Red Tide on the Pacific Coast of Mexico. Marine Environmental Research 1986; 19: 77-92.

  64. 64.- Saldate-Castañeda O, Vázquez-Castellanos JL, Galván J, Sánchez-Anguiano A, Nazar A. Intoxicaciones por toxina paralizante de molusco en Oaxaca. Salud Pública Mex 1991; 33: 240-7.

  65. 65.- Ronsón-Paulín, JA. Análisis retrospectivo y posibles causas de mareas rojas tóxicas en el litoral del sureste mexicano (Guerrero, Oaxaca, Chiapas). Ciencias del Mar. 1999; 9: 40-56.

  66. 66.- Cortés-Lara MC. Informe del fenómeno de marea roja en Bahía Banderas Jalisco-Nayarit, octubre- noviembre 2001. Rev Biomed 2002; 13: 73-5.

  67. 67.- Cortés-Altamirano R, Muñoz-Cabrera L, Sotomayor-Navarro O. Envenenamiento Paralítico por mariscos (PSP), causado por el dinoflagelado Pyrodinium bahamense var. compressum en la costa suroeste de México. Anales del Instituto de Ciencias del Mar y Limnología 1993; 20: 43-54.

  68. 68.- Cortés Altamirano R, Alonso Rodríguez R. Mareas rojas por Gymnodinium catenatum en Mazatlán 1997. Ciencias del Mar UAS 1999; 15: 31-7.

  69. 69.- Sierra-Beltrán AP, Cruz A, Núñez E, Del Villar M, Cerero J, Ochoa JL. An overview of the marine food poisoning in México. Toxicon 1998; 36: 1493-502.

  70. 70.- Gárate-Lizárraga I, Bustillos-Guzmán JJ, Alonso-Rodríguez R, Luckas B. Comparative paralytic shellfish toxin profiles in two marine bivalves during outbreaks of Gymnodinium catenatum (Dinophyceae) in the Gulf of California. Marine Pollution Bulletin 2004; 48: 397-402.

  71. 71.- Ochoa JL, Hernández-Becerril DU, Lluch-Cota S, Arredondo-Vega BO, Núñez-Vázquez E, Heredia-Tapia A, et al. Marine biotoxins and harmgul algal blooms in Mexico's Pacific litoral En: Taylor M, Trainer VL, editores. Harmful algal blooms in the PICES region of the North Pacific. PICES Scientific Report N°23 North Pacific Scie. 2002.

  72. 72.- Franco JM, Fernández-Villa P. Separation of Paralytic Shellfish toxins by reverserd phase high performance liquid chromatography, with postcolumn reaction and fluorimetric detection. Cromatographia 1993; 35: 613-20.

  73. 73.- Hay BE, Grant CM, McCoubrey DJ. A Review of the marine biotoxin monitorin programme for non-commercially harvested shellfish. Part 1: Technical report. A report prepared for the NZ Ministry of Health by AquaBio Consultants Ltd. NZ Ministry of Health 2000.

  74. 74.- Baden GD, Fleming LE, Bean JA. Marine Toxins. En: De Wolff FA editor. Handbook of Clinical Neurology: Intoxications of the Nervous System. Amsterdan: Elsevier Publishing; 1995. p. 141-75.

  75. 75.- Luke Y, Dart RC. Food Poisoning-Shellfish. En: Dart RC editor. 5 minute toxicology Consultan. London: Lippincott, Williams & Wilkins 2000. p. 392-3.

  76. 76.- Harris JB, Goonetilleke A. Animal poisons and the nervous system: what the neurologist needs to know. J Neurol Neurosurg Psychiatry 2004; 75 (Suppl III) iii40-iii46.

  77. 77.- Gessner BD, Bell P, Doucette GJ, Mocczydlowski E, Poli MA, Van Dolah F, Hall S. Hypertension and identification of toxin in human urine and serum following a cluster o mussel-associated paralytic shellfish poisoning outbreaks. Toxicon 1997; 35: 711-22.

  78. 78.- Wallace BJ, Guzewich JJ, Cambridge M, Altekruse S, Morse DL. Seafood-Associated Disease Outbreaks in New York, 1980-1994. Am J Prev Med 1999; 17: 48-54.

  79. 79.- De Carvalho M, Jacinto J, Ramos N, De Oliveira V, Pinho T, Joao de Sá M. Paralytic shellfish poisoning:clinical and electrophysiological observations. J Neurol 1998; 245: 551-4.

  80. 80.- Long RR, Sargent JC, Hammer K. Paralytic shellfish poisoning: a case report and serial electrophysiologic observations. Neurology 1990; 40: 1310-2.

  81. 81.- Cheng HS, Chua SO, Hung JS, Yip KK. Creatin kinase MB elevation in paralytic shellfish poisoning. Chest 1991; 99: 1032-3.

  82. 82.- Mahmud Y, Arakawa O, Noguchi T. An epidemic survey on freswater puffer poisoning in Bangladesh. J Nat Toxins 2000; 9 ; 319-26.

  83. 83.- Isbister GK, Kiernan MC. Neurotoxic marine poisoning. Lancet Neurology 2005; 4: 219-28.

  84. 84.- Negoro K, Morimatsu M. Clinical analysis of paralytic shellfish poisoning following ingestion of oysters. Rinsho Shinkeigaku 1993; 33: 207-9.

  85. 85.- Kan SK, Singh N, Chan MK. Oliva vidua fulminans, a marine mollusk, responsible for five fatal cases of neurotoxic food poisoning in Sabah, Malaysia. Trans R Soc Trop Med Hyg 1986; 80:64-5.

  86. 86.- García C, Bravo MC, Lagos M, Lagos N. Paralytic shellfish poisoning: post-mortem analysis of tissue and body fluid samples from human victims in the Patagonia fjords. Toxicon 2004; 43: 149-58.

  87. 87.- Duncan KG, Duncan JL, Schwartz DM. Saxitoxin: An anesthetic of the deepithelialized rabbit cornea. Cornea 2001; 20: 639-42.

  88. 88.- Montebruno D. Poisoning by the consumption of shellfish contaminated with paralytic venom in the XII Region, Chile. Anatomopathological study. Rev Med Chil 1993; 121: 94-7.

  89. 89.- Garrido R, Lagos N, Lattes K, Azolas CG, Bocic G, Cuneo A, et al. The gonyautoxin 2/3 epimer reduces anal tone when inyected in the anal sphincter of healthy adults. Biol Res 2004; 37: 395-403.

  90. 90.- Graham HW. Gymnodinium catenatum a new dinoflagellate from the Gulf of California. Trans Am Microscop Soc 1943; 62: 259-61.

  91. 91.- Sierra-Beltrán AP, Morquecho-Escamilla ML, Lechuga-Devéze C, Ochoa JL. PSP monitoring program at Baja California Sur, Mexico. En Yasumoto T, Oshima Y, Fukuyo Y, editores. Harmful and Toxic Algal Blooms. Intergovernmental Oceanographic Commission of UNESCO, Paris. 1996. p. 105- 8.

  92. 92.- Orellana-Cepeda E, Martínez-Romero E, Muñoz-Cabrera L, López-Ramírez P, Cabrera-Mancilla E, Ramírez-Camarena C. Toxicity associated with blooms of Pyridinium bahamense var. compressum in south western México. En: Reguera B, Blanco J, Fernández M L, Wyatt T, editores. Harmful Algae. Xunta de Galicia, IOC 1998. p. 60.

  93. 93.- Gárate-Lizárraga I, Hernández-Orozco ML, Band-Schmidt C, Serrano-Casillas G. Red tides along the coasts of Baja California Sur, México (1984 to 2001). Oceánides 2001; 16: 127-34.

  94. 94.- Gárate-Lizárraga I, Bustillos-Guzmán JJ, Erler K, Muñeton-Gómez MS, Luckas B. Tripp-Quezada A. Paralytic shellfish toxins in the chocolata clam, Megapitaria squalida (Bivalvia: Veneridae), in Bahía de La Paz, Gulf of California. Rev Biol Trop 2004; 52: 133-40.

  95. 95.- Band-Schmidt CJ, Bustillos-Guzmán J, Gárate-Lizárraga I, Lechuga-Devéze CH, Reinhardt K, Luckas B. Profiles of paralytic shellfish toxin in strains of the dinoflagellate Gymnodinium catenatum and the scallop Argopecten ventricosus from Bahía Concepción, Gulf of California, Mexico. Harmful Algae 2005; 4: 21-31.

  96. 96.- Gárate-Lizárraga I, Bustillos-Guzmán JJ, Morquecho M, Band-Schmidt CJ, Alonso-Rodriguez R, Erler K, et al. Comparative paralytic shellfish toxin profiles in the strains of Gymnodinium catenatum Graham from the Gulf of California, Mexico. Marine Pollution Bulletin 2005; 50: 213-9.

  97. 97.- Cifuentes-Lemus J.L, Torres-García P, Frías-M M. El Océano y La pesca. IX. La Pesca. México: Fondo de Cultura Económica; Segunda Edición 1997. pp. 125.

  98. 98.- Cifuentes-Lemus J.L, Torres-García P, Frías-M M. El Océano y sus recursos X. Las pesquerías. Fondo de Cultura Económica, Segunda Edición, México, D.F. 1997 pp 130.

  99. 99.- Whittle K Gallacher S. Marine toxins Health and the food-chain. Br Med Bull 2000; 56:236-53.

  100. 100.- Bicelj VM, Connell L, Konoki K, Macquarrie SP, Scheuer T, Catterall WA, Trainer VL. Nature 2005; 434:716.

  101. 101.- Cortés-Altamirano, RA, Sierra-Beltrán P., Cortés-Lara M. C. 2004. Dominance and permanence of species of harmful algae forming blooms in Mazatlán Bay, Mexico (1979-2002). En: Steidinger, K. A., J. H. Landsberg, C. R. Tomas & G. A. Vargo, editors. Harmful Algae 2002. Xth International Conference, St. Pete Beach, Florida, USA, October 21-25, 2002. Florida Fish and Wildlife Conservation Commission, Florida Institute of Oceanography, and Intergovernmental Oceanographic Commission of UNESCO; 2004. p. 344-6.




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