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Órgano Oficial de la Asociación Mexicana de Hepatología

2006, Number S1

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Ann Hepatol 2006; 5 (S1)

Module Xl
Treatment of HCV and HIV coinfection

Juárez NJA

Language: English
References: 99
Page: 42-48
PDF size: 73.05 Kb.


Text Extraction

Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and 1.8% of the population of the USA. The principal route of transmission before the 1990s was transfusion of blood and blood derivatives. At present, the prevalence of chronic infection is greater than 60% in patients with hematological dysfunctions (hemophilia, thalassemia), renal diseases requiring hemodialysis or transplantation, and indinavirassociated renal complications. However, transmission by transfusion has been substantially reduced by the implementation of laws that require all blood donors to be tested for the presence of anti-HCV antibodies. The incidence of chronic HCV infection is greater than 80% among people addicted to intravenous drugs and among people with human immunodeficiency syndrome.
HCV and human immunodeficiency virus (HIV) coinfection is common in patients who acquire HIV by parenteral routes. Increased survival rates in patients with HIV resulting from the use of highly active antiretroviral therapy (HAART) and faster development of liver cirrhosis in patients with HIV have made treatment of chronic hepatitis C a priority in patients with HIV coinfection.


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