medigraphic.com
Revista Mexicana de Coloproctología Enfermedades del Ano, Recto y Colon

2007, Number 2

<< Back Next >>

Rev Mex Coloproctol 2007; 13 (2)

Management of perianal condylomata acuminata

Pimentel CG, Manterola ÁD

Language: Spanish
References: 30
Page: 42-47
PDF size: 158.27 Kb.


ABSTRACT

Perianal condylomatosis is one of the most frequent sexual transmitted diseases and it is caused by the human papillomavirus. Most of the patients with this condition have the antecedent of anal intercourse, and the presence of the human papillomavirus is strongly related with immunosuppression associated with human immunodeficiency virus. Many treatments had been used and proposed, but none of them offers complete resolution of the disease because they are associated with significant recurrence rates. The use of imiquimod and podofilox is very effective in small lesions. Surgical excision is preferred in bigger lesions and in combination with other treatments such as electrocoagulation, cryotherapy and CO2 laser vaporization. The use of imiquimod, interferon and immunotherapy is combined for avoiding recurrences. It is recommended to combine the treatments and to follow-up the patients, mainly during the first three months, which is the period of greater recurrence.


REFERENCES

  1. Wienert V. Virus induced anorectal diseases. Condylomata acuminata and herpes simplex. Hautarzt 2004; 55: 248-53.

  2. Lu Y, Wang XL et al. Clinical features and epidemiological survey of perianal warts in 72 males. Zhongua Nan Ke Xue 2006; 12: 923-6.

  3. Koutsky L. Condylomata acuminata (genital warts): patient demographics and treating physicians. Am J Med 1997; 102: 3-8.

  4. Vargas CJ. Avances sobre la infección por papilomavirus en la patología humana y su relación con las neoplasias malignas anorrectales. Rev Mex Coloproctol 1995; 1: 24.

  5. Lajous et al. Determinants of prevalence, acquisition and persistence of human papillomavirus in healthy mexican military men. Cancer Epidemiol Biomarkers Prev 2005; 14: 1710-6.

  6. Van Howe, RS, Hodges, FM. The carcinogenicity of smegma: debunking a myth. J Eur Acad Derm Vener 2006; 20: 1046-54.

  7. Sánchez VG, Vieyra FJ, Pena JP, Villanueva SE. Anorectal diseases in HIV positive patients. A prospective study. Rev Gastr Mex 1998; 63: 89-92.

  8. Friedman, Scott L et al. Diseases of the colon and rectum. In: Current Diagnosis & Treatment in Gastroenterology. 2nd Ed. McGraw-Hill. 2003: 474.

  9. Gonzalez RC, Heartfield W, Briggs B, Vukasin P, Beart RW. Anorectal pathology in HIV/AIDS infected patients has not been impacted by highly active antiretroviral therapy. Dis Colon Rectum 2004; 9: 1483-6.

  10. Anderson CA et al. Anal condyloma: a comparison between HIV positive and negative patients. Am Surg 2004; 70: 1014-8.

  11. Papaconstantinou HT, Lee AJ et al. Screening methods for high-grade dysplasia in patients with anal condyloma. J Surg Rev 2005; 1: 8-13.

  12. Kodner CM, Nasraty S. Management of Genital Warts. Am Fam Physician 2004; 70: 2335-42, 2345-6.

  13. Bonnez W, Oakes D, Choi A et al. Therapeutic efficacy and complications of excisional biopsy of condyloma acuminatum. Sex Transm Dis 1996; 23: 273-76.

  14. Duus BR, Philipsen T, Christensen JD et al. Refractory condylomata acuminata: A controlled clinical trial of carbon dioxide laser versus conventional surgical treatment. Genitourin Med 1985; 61: 59-61.

  15. Kaspari M et al. Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma. Br J Dermatol 2002; 147: 757-9.

  16. De la Fuente BG et al. Preoperative immune status determines anal condiloma recurrence after surgical excision. Dis Colon Rectum 2003; 46: 367-73.

  17. Pfenninger JL, Zainea GG. Common anorectal conditions: Part II. Lesions. Am Fam Physician 2001; 64: 77-88.

  18. Simmons PD, Langlet F, Thin RN. Cryotherapy versus electrocautery in the treatment of genital warts. Br J Vener Dis 1981; 57: 273-4.

  19. Ammori BJ, Ausobsky JR. Electrocoagulation of perianal warts: a word of caution. Dig Surg 2000; 17: 296-7.

  20. Davis BE, Noble MJ. Initial experience with combined interferona2b and carbon dioxide laser for the treatment of condylomata acuminata. J Urol 1992; 147: 627-9.

  21. Perisic Z et al. Condylomata gigantea in anal and perianal region: surgical and CO2 laser treatment. Arch Gynecol Obstet 2003; 267: 263-5.

  22. Ferenczy A, Bergeron C, Richart RM. Human papillomavirus DNA in CO2 laser-generated plume of smoke and its consequences to the surgeon. Obstet Gynecol 1990; 75: 114-8.

  23. Culp OS, Kaplan IW. Condylomata acuminata: Two hundred cases treated with podophyllin. Ann Surg 1944; 120: 251.

  24. Strand A, Brinkeborn RM, Siboulet A. Title tropical treatment of genital warts in men, an open study of podophyllotoxin cream compared with solution. Genitourinary Med 1995; 71: 387-390.

  25. Tyring S, Conant M et al. Imiquimod an international update on therapeutic uses in dermatology. Int J Derm 2002; 41: 810-816.

  26. Abcarian H, Sharon N. The effectiveness of immunotherapy in the treatment of anal condyloma acuminatum. J Surg Rev 1977; 22: 231.

  27. Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention. MMWR Recomm Rep. 2002; 51: 1-80.

  28. Armstrong DK, Maw RD, Dinsmore WW, Morrison GD, Pattman RS, Watson PG, Nathan PM, Moss T, Nayagam A, Wade A. A randomized, double-blind, parallel group study to compare subcutaneous interferon alpha-2a plus podophyllin with placebo plus podophyllin in the treatment of primary condylomata acuminata. Genitourin Med 1994; 70: 389-93.

  29. Alam M, Stiller M. Direct medical costs for surgical and medical treatment of condylomata acuminata. Arch Dermatol 2001; 137: 337-41.

  30. Wiley DJ, Harper DM et al. How condom use, number of receptive anal intercourse partners and history of external genital warts predict risk for external anal warts. Int J STD AIDS 2005; 16: 203-11.




2020     |     www.medigraphic.com