2007, Number 3
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Med Cutan Iber Lat Am 2007; 35 (3)
Erradication of Helicobacter pylori infection and clinical response of chronic idiopathic urticaria
Marcano-Lozada MJ, Urrestarazu MI, Serrano MN
Language: Spanish
References: 30
Page: 130-135
PDF size: 219.72 Kb.
ABSTRACT
Background: helicobacter pylori chronic colonization in the human host is associated with peptic ulcer and cancer development an recently with many extragastric disease. Our main goal is to demonstrate that
H. pylori is associated with the dermatological disease chronic idiopathic urticaria (CIU).
Material & methods: We studied 60 patients with CIU diagnosis at baseline and 6 weeks after therapeutic intervention to eradicate
H. pylori in the infected patients.
H. pylori status was established by UBT-C14, and we performed clinical interrogation and evaluation at each time.
Results: 44 patients were UBT-positive and 16 UBT-negative, no statistically significant differences were founded in the mean age, gender, duration of disease, and symptoms between both groups. A statistically significant clinical improvement of CIU symptoms was find in the UBT-positive patients after
H. pylori successful eradication (100%) compared with UBT-negative patients (P ‹ 0.0001).
Conclusion: Successful eradication of
H. pylori correlated with clinical improvement of CIU symptoms, these findings strengthen the role of
H. pylori in the maintenance of CIU disease.
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