2006, Number 4
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salud publica mex 2006; 48 (4)
Triglycerides and high-density lipoprotein cholesterol are associated with insulinemia in adolescents
Ramírez-López G, González-Villalpando C, Salmerón J, González-Ortiz M, Valles-Sánchez V
Language: English
References: 37
Page: 293-299
PDF size: 104.75 Kb.
ABSTRACT
Objective. The aim of this study was to evaluate the association between lipids and insulin concentration in adolescents.
Material and Methods. A cross-sectional study of 350 adolescents aged 14-19 years old from a public high school in Guadalajara, in the state of Jalisco, Mexico, was conducted. Fasting insulin concentration was determined using microparticle enzyme immunoassay; total cholesterol and triglycerides were detected by standard enzymatic procedures; and low- and high-density lipoproteins were found using standard precipitation methods. Statistical analysis included linear multivariate regression.
Results. Serum triglycerides were associated positively with insulin fasting (β= 0.003,
p= 0.0001) and high-density lipoprotein cholesterol was negatively associated with insulin fasting in male adolescents 18-19 years old (β= -0.03,
p= 0.012).
Conclusions. The relationships between triglycerides and insulin and between high-density lipoprotein cholesterol and insulin are already present in adolescence.
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