2022, Number 3
Heberprot-P in the treatment of diabetic foot ulcers
Language: Spanish
References: 12
Page:
PDF size: 255.29 Kb.
ABSTRACT
Introduction: The diabetic foot is one of the most feared complications of diabetes mellitus; It is the cause of 80 % of non-traumatic amputations worldwide. For decades, different treatments have been used to heal diabetic foot; growth factors have revolutionized this therapy. The participation of a multidisciplinary team with compliance with the action protocols and the use of Heberprot-P decrease the rate of amputations in patients with this condition.Objective: To present the evolution of patients with diabetic foot ulcers, in different clinical stages, treated with Heberprot-P.
Development: Three clinical cases are presented; The first is a male patient, 56 years old, diabetic, with open transmetatarsal amputation in which 16 applications of Heberprot-P were performed and a skin graft was placed, the lesion closed in 45 days. The second is a 58-year-old patient, diabetic and hypertensive, with a right foot injury, with previous vascular surgery; 19 applications of Heberprot-P were performed and the lesion healed in 49 days. The third case is a 55-year-old patient, who was admitted due to an extensive injury to his right foot, 22 applications of Heberprot-P were performed, closure of the injury was achieved in 85 days and amputation was avoided.
Conclusions: The presented cases evolved favorably with Heberprot-P treatment.
REFERENCES
Escobar Amarales Y, Torres Romo UR, Escalante Padrón O, Fernández Franch N, Ibarra Viena V, Miranda Rodríguez E. El Heberprot-P(r) en el tratamiento de úlceras del pie diabético. AMC. 2014 [acceso: 11/01/2022]; 18(3):[aprox. 10 p]. Disponible en: Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552014000300005 6.
Fernández-Montequín JI, Valenzuela-Silva CM, González Díaz O, Savigne W, Sancho Soutelo N, Rivero Fernández F, et al. Intra-lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo-controlled double-blind study. International Wound Journal. 2009; 6(6): 432-43. DOI: 10.1111/j.1742-481X.2009.00641.x12.