2024, Number 4
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Lat Am J Oral Maxillofac Surg 2024; 4 (4)
Clinical challenges in denosumab osteonecrosis: an effective conservative approach
Cuen-Lara E, Reyes-Torres G, Palacios-Solís DA
Language: Spanish
References: 22
Page: 144-149
PDF size: 332.49 Kb.
ABSTRACT
Denosumab-induced osteonecrosis is a possible side effect of up to 15% in patients using this drug, which is mainly indicated to treat bone problems related to osteoporosis or malignant neoplasms. Its onset and treatment can be complex because it can sometimes be underdiagnosed, causing the disease to progress. Treatment can range from conservative means to invasive procedures. This article presents a clinical case of a patient with denosumab-induced osteonecrosis after bone extraction. Despite presenting purulent exudate and signs of infection, the patient was treated and resolved conservatively with antibiotic therapy and chlorhexidine to subsequently remove the bone sequestration, highlighting the importance of timely follow-up and adherence, avoiding morbid procedures.
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